Probing Secondary Carbohydrate−Protein Interactions with Highly Dense Cyclodextrin-Centered Heteroglycoclusters: The Heterocluster Effect
Comparison of the lectin-binding properties for highly dense β-cyclodextrin-centered homo- and heteroglycoclusters with defined architecture provides evidence for the existence of strong synergic effects (heterocluster effect) on carbohydrate−protein recognition events.
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| Veröffentlicht in: | Journal of the American Chemical Society 2005-06, Vol.127 (22), p.7970-7971 |
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| container_end_page | 7971 |
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| container_issue | 22 |
| container_start_page | 7970 |
| container_title | Journal of the American Chemical Society |
| container_volume | 127 |
| creator | Gómez-García, Marta Benito, Juan M. Rodríguez-Lucena, David Yu, Jian-Xin Chmurski, Kazimierz Ortiz Mellet, Carmen Gutiérrez Gallego, Ricardo Maestre, Alfredo Defaye, Jacques García Fernández, José M. |
| description | Comparison of the lectin-binding properties for highly dense β-cyclodextrin-centered homo- and heteroglycoclusters with defined architecture provides evidence for the existence of strong synergic effects (heterocluster effect) on carbohydrate−protein recognition events. |
| doi_str_mv | 10.1021/ja050934t |
| format | Article |
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Associations ; Intermolecular phenomena ; Lactose - chemistry ; Lactose - metabolism ; Life Sciences ; Mannose - chemistry ; Mannose - metabolism ; Models, Molecular ; Molecular biophysics ; Pharmaceutical sciences ; Thermodynamics</subject><ispartof>Journal of the American Chemical Society, 2005-06, Vol.127 (22), p.7970-7971</ispartof><rights>Copyright © 2005 American Chemical Society</rights><rights>2005 INIST-CNRS</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a415t-4843e3360f233cbb73ae212001abec72b108d7c1c4c414faa34bfb61fc78b94d3</citedby><cites>FETCH-LOGICAL-a415t-4843e3360f233cbb73ae212001abec72b108d7c1c4c414faa34bfb61fc78b94d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/ja050934t$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/ja050934t$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>230,314,776,780,881,2752,27053,27901,27902,56713,56763</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16856892$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15926794$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00384640$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Gómez-García, Marta</creatorcontrib><creatorcontrib>Benito, Juan M.</creatorcontrib><creatorcontrib>Rodríguez-Lucena, David</creatorcontrib><creatorcontrib>Yu, Jian-Xin</creatorcontrib><creatorcontrib>Chmurski, Kazimierz</creatorcontrib><creatorcontrib>Ortiz Mellet, Carmen</creatorcontrib><creatorcontrib>Gutiérrez Gallego, Ricardo</creatorcontrib><creatorcontrib>Maestre, Alfredo</creatorcontrib><creatorcontrib>Defaye, Jacques</creatorcontrib><creatorcontrib>García Fernández, José M.</creatorcontrib><title>Probing Secondary Carbohydrate−Protein Interactions with Highly Dense Cyclodextrin-Centered Heteroglycoclusters: The Heterocluster Effect</title><title>Journal of the American Chemical Society</title><addtitle>J. Am. Chem. Soc</addtitle><description>Comparison of the lectin-binding properties for highly dense β-cyclodextrin-centered homo- and heteroglycoclusters with defined architecture provides evidence for the existence of strong synergic effects (heterocluster effect) on carbohydrate−protein recognition events.</description><subject>beta-Cyclodextrins - chemistry</subject><subject>beta-Cyclodextrins - metabolism</subject><subject>Biological and medical sciences</subject><subject>Carbohydrate Conformation</subject><subject>Carbohydrate Metabolism</subject><subject>Carbohydrates - chemistry</subject><subject>Concanavalin A - chemistry</subject><subject>Concanavalin A - metabolism</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glucose - chemistry</subject><subject>Glucose - metabolism</subject><subject>Interactions. Associations</subject><subject>Intermolecular phenomena</subject><subject>Lactose - chemistry</subject><subject>Lactose - metabolism</subject><subject>Life Sciences</subject><subject>Mannose - chemistry</subject><subject>Mannose - metabolism</subject><subject>Models, Molecular</subject><subject>Molecular biophysics</subject><subject>Pharmaceutical sciences</subject><subject>Thermodynamics</subject><issn>0002-7863</issn><issn>1520-5126</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0LtuFDEUBmALgcgSKHgB5IaCYhLf5kYXTS4baRARWUCisWyPZ8fLZBzZXsh0KUNDkUfMk-DVjnYbKuuc8_nI_gF4i9ERRgQfrwRKUUlZeAZmOCUoSTHJnoMZQogkeZHRA_DK-1UsGSnwS3CA05Jkeclm4O-Vs9IMS3itlR0a4UZYCSdtNzZOBP308BhB0GaAl0PQTqhg7ODhbxM6ODfLrh_hqR68htWoetvou-DMkFR6g3UD5zqedtmPyqp-7WPhPz7d_4GLTk-zqQ3P2lar8Bq8aEXv9ZvpPARfz88W1TypP19cVid1IhhOQ8IKRjWlGWoJpUrKnApNMEEIC6lVTiRGRZMrrJhimLVCUCZbmeFW5YUsWUMPwYft3k70_NaZm_hxboXh85Oab3oI0YJlDP3Ce6uc9d7pdncBI77Jn-_yj_bd1t6u5Y1u9nIKPIL3ExBeib51YlDG711WpFlRkuiSrTMxnbvdXLifPMtpnvLF1TX__uPLp_NvNeL1fq9Qnq_s2g0xvv888B8rIa09</recordid><startdate>20050608</startdate><enddate>20050608</enddate><creator>Gómez-García, Marta</creator><creator>Benito, Juan M.</creator><creator>Rodríguez-Lucena, David</creator><creator>Yu, Jian-Xin</creator><creator>Chmurski, Kazimierz</creator><creator>Ortiz Mellet, Carmen</creator><creator>Gutiérrez Gallego, Ricardo</creator><creator>Maestre, Alfredo</creator><creator>Defaye, Jacques</creator><creator>García Fernández, José M.</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>1XC</scope></search><sort><creationdate>20050608</creationdate><title>Probing Secondary Carbohydrate−Protein Interactions with Highly Dense Cyclodextrin-Centered Heteroglycoclusters: The Heterocluster Effect</title><author>Gómez-García, Marta ; Benito, Juan M. ; Rodríguez-Lucena, David ; Yu, Jian-Xin ; Chmurski, Kazimierz ; Ortiz Mellet, Carmen ; Gutiérrez Gallego, Ricardo ; Maestre, Alfredo ; Defaye, Jacques ; García Fernández, José M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a415t-4843e3360f233cbb73ae212001abec72b108d7c1c4c414faa34bfb61fc78b94d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>beta-Cyclodextrins - chemistry</topic><topic>beta-Cyclodextrins - metabolism</topic><topic>Biological and medical sciences</topic><topic>Carbohydrate Conformation</topic><topic>Carbohydrate Metabolism</topic><topic>Carbohydrates - chemistry</topic><topic>Concanavalin A - chemistry</topic><topic>Concanavalin A - metabolism</topic><topic>Fundamental and applied biological sciences. 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Am. Chem. Soc</addtitle><date>2005-06-08</date><risdate>2005</risdate><volume>127</volume><issue>22</issue><spage>7970</spage><epage>7971</epage><pages>7970-7971</pages><issn>0002-7863</issn><eissn>1520-5126</eissn><coden>JACSAT</coden><abstract>Comparison of the lectin-binding properties for highly dense β-cyclodextrin-centered homo- and heteroglycoclusters with defined architecture provides evidence for the existence of strong synergic effects (heterocluster effect) on carbohydrate−protein recognition events.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>15926794</pmid><doi>10.1021/ja050934t</doi><tpages>2</tpages></addata></record> |
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| subjects | beta-Cyclodextrins - chemistry beta-Cyclodextrins - metabolism Biological and medical sciences Carbohydrate Conformation Carbohydrate Metabolism Carbohydrates - chemistry Concanavalin A - chemistry Concanavalin A - metabolism Fundamental and applied biological sciences. Psychology Glucose - chemistry Glucose - metabolism Interactions. Associations Intermolecular phenomena Lactose - chemistry Lactose - metabolism Life Sciences Mannose - chemistry Mannose - metabolism Models, Molecular Molecular biophysics Pharmaceutical sciences Thermodynamics |
| title | Probing Secondary Carbohydrate−Protein Interactions with Highly Dense Cyclodextrin-Centered Heteroglycoclusters: The Heterocluster Effect |
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