α-Helical Coiled-coil Oligomerization Domains Are Almost Ubiquitous in the Collagen Superfamily

α-Helical coiled coils are widely occurring protein oligomerization motifs. Here we show that most members of the collagen superfamily contain short, repeating heptad sequences typical of coiled coils. Such sequences are found at the N-terminal ends of the C-propeptide domains in all fibrillar proco...

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Veröffentlicht in:	The Journal of biological chemistry 2003-10, Vol.278 (43), p.42200-42207
Hauptverfasser:	McAlinden, Audrey, Smith, Thomasin A., Sandell, Linda J., Ficheux, Damien, Parry, David A.D., Hulmes, David J.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biochemistry, Molecular Biology Collagen - chemistry Fibrillar Collagens - chemistry Humans Life Sciences Models, Molecular Peptide Fragments - chemistry Procollagen - chemistry Protein Structure, Secondary Protein Structure, Tertiary Recombinant Fusion Proteins Repetitive Sequences, Amino Acid Sequence Alignment von Willebrand Factor - chemistry
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