Dynamical analysis of a generic Boolean model for the control of the mammalian cell cycle

Motivation: To understand the behaviour of complex biological regulatory networks, a proper integration of molecular data into a full-fledge formal dynamical model is ultimately required. As most available data on regulatory interactions are qualitative, logical modelling offers an interesting frame...

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Veröffentlicht in:	Bioinformatics 2006-07, Vol.22 (14), p.e124-e131
Hauptverfasser:	Fauré, Adrien, Naldi, Aurélien, Chaouiya, Claudine, Thieffry, Denis
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Cycle - physiology Cell Cycle Proteins - metabolism Cellular Biology Computer Simulation Gene Expression Regulation - physiology Humans Kinetics Life Sciences Logistic Models Models, Biological Regulatory Elements, Transcriptional - physiology Signal Transduction - physiology Transcription Factors - metabolism
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