Highly Efficient Synthesis of β(1 → 4)-Oligo- and -Polysaccharides Using a Mutant Cellulase

This report describes an efficient chemoenzymatic synthesis of a variety of regioselectively modified β(1→4)-oligo- and -polysaccharides. This successful approach was based on:  (i) the use of a “glycosynthase” which is a Glu-197-Ala nucleophile mutant of the retaining cellulase endoglucanase I (Cel...

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Veröffentlicht in:	Journal of the American Chemical Society 2000-06, Vol.122 (23), p.5429-5437
Hauptverfasser:	Fort, Sébastien, Boyer, Viviane, Greffe, Lionel, Davies, Gideon J, Moroz, Olga, Christiansen, Lars, Schülein, Martin, Cottaz, Sylvain, Driguez, Hugues
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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