Oxytocin Controls Differentiation of Human Mesenchymal Stem Cells and Reverses Osteoporosis

Osteoporosis constitutes a major worldwide public health burden characterized by enhanced skeletal fragility. Bone metabolism is the combination of bone resorption by osteoclasts and bone formation by osteoblasts. Whereas increase in bone resorption is considered as the main contributor of bone loss...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2008-09, Vol.26 (9), p.2399-2407
Hauptverfasser:	Elabd, Christian, Basillais, Armelle, Beaupied, Hélène, Breuil, Véronique, Wagner, Nicole, Scheideler, Marcel, Zaragosi, Laure‐Emmanuelle, Massiéra, Florence, Lemichez, Emmanuel, Trajanoski, Zlatko, Carle, Georges, Euller‐Ziegler, Liana, Ailhaud, Gérard, Benhamou, Claude‐Laurent, Dani, Christian, Amri, Ez‐Zoubir
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocyte Adipogenesis Aged Aged, 80 and over Animals Biochemistry, Molecular Biology Bone Marrow Cells - drug effects Bone Marrow Cells - metabolism Bone Marrow Cells - pathology Cells, Cultured Child, Preschool Development Biology Differentiation Female Humans Life Sciences Male Mesenchymal stem cells Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - pathology Mice Middle Aged Osteoblast Osteoblasts - metabolism Osteoblasts - pathology Osteoclasts - drug effects Osteoclasts - metabolism Osteoclasts - pathology Osteogenesis Osteoporosis Osteoporosis - metabolism Osteoporosis - pathology Osteoporosis - therapy Osteoporosis, Postmenopausal - blood Ovariectomy Oxytocin Oxytocin - analogs & derivatives Oxytocin - blood Oxytocin - pharmacology Oxytocin - physiology Rats Receptors, Oxytocin - metabolism
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