Intraretinal RGMa is involved in retino-tectal mapping

The repulsive guidance molecule (RGMa) is involved in controlling the topography of retinal ganglion cell axons along the anterioposterior axis of the tectum. Here, we generated a new RGMa-monoclonal antibody and show that it is expressed in the developing retina, suggesting that it may regulate ret...

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Veröffentlicht in:	Molecular and cellular neuroscience 2008-04, Vol.37 (4), p.761-769
Hauptverfasser:	Tassew, Nardos G., Chestopolava, Larisa, Beecroft, Robert, Matsunaga, Eiji, Teng, Henry, Chedotal, Alain, Monnier, Philippe P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axon guidance Brain Mapping - methods Cells, Cultured Cercopithecus aethiops Chick Embryo Chickens Cognitive science COS Cells DiI labeling GPI-Linked Proteins Life Sciences Mice Mice, Inbred BALB C Nerve Tissue Proteins - genetics Nerve Tissue Proteins - physiology Neurons and Cognition Neuroscience Pathfinding Repulsive Guidance Molecule RGMa Retina Retina - embryology Retina - physiology Retino-tectal projection RNA interference Superior Colliculi - embryology Superior Colliculi - physiology Tectum Visual Pathways - embryology Visual Pathways - physiology
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