Global disease spread: Statistics and estimation of arrival times

We study metapopulation models for the spread of epidemics in which different subpopulations (cities) are connected by fluxes of individuals (travelers). This framework allows one to describe the spread of a disease on a large scale and we focus here on the computation of the arrival time of a disea...

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Veröffentlicht in:Journal of theoretical biology 2008-04, Vol.251 (3), p.509-522
Hauptverfasser: Gautreau, Aurélien, Barrat, Alain, Barthélemy, Marc
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container_title Journal of theoretical biology
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creator Gautreau, Aurélien
Barrat, Alain
Barthélemy, Marc
description We study metapopulation models for the spread of epidemics in which different subpopulations (cities) are connected by fluxes of individuals (travelers). This framework allows one to describe the spread of a disease on a large scale and we focus here on the computation of the arrival time of a disease as a function of the properties of the seed of the epidemics and of the characteristics of the network connecting the various subpopulations. Using analytical and numerical arguments, we introduce an easily computable quantity which approximates this average arrival time. We show on the example of a disease spread on the world-wide airport network that this quantity predicts with a good accuracy the order of arrival of the disease in the various subpopulations in each realization of epidemic scenario, and not only for an average over realizations. Finally, this quantity might be useful in the identification of the dominant paths of the disease spread.
doi_str_mv 10.1016/j.jtbi.2007.12.001
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subjects Aircraft
Biometry - methods
Communicable Disease Control
Communicable Diseases, Emerging - transmission
Complex networks
Condensed Matter
Disease Outbreaks - statistics & numerical data
Disease Transmission, Infectious
Epidemiology
Genetics
Global Health
Humans
Life Sciences
Physics
Populations and Evolution
Statistical Mechanics
Stochastic Processes
Travel
World airport network
title Global disease spread: Statistics and estimation of arrival times
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