Flagellar length depends on LdARL-3A GTP/GDP unaltered cycling in Leishmania amazonensis

We have shown previously that expression of the GTP-blocked form of the small G protein LdARL-3A/Q70L led to a marked shortening of Leishmania promastigotes flagella. In contrast, there was no effect with the T30N mutant, thought to represent the GDP-blocked form. However, recent data, obtained with...

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Veröffentlicht in:	Molecular and biochemical parasitology 2008, Vol.157 (1), p.83-87
Hauptverfasser:	Sahin, Annelise, Espiau, Benoît, Marchand, Cécile, Merlin, Gilles
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution - genetics Animals Differentiation Flagella - genetics Flagella - physiology Flagellar length G protein cycle Guanosine Diphosphate - metabolism Guanosine Triphosphate - metabolism LdARL-3A Leishmania Leishmania - cytology Leishmania - genetics Leishmania - physiology Life cycle Life Sciences Microbiology and Parasitology Microscopy, Fluorescence Microscopy, Phase-Contrast Protozoan Proteins - genetics Protozoan Proteins - metabolism
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