Neuronal calcium sensor‐1 gene ncs‐1a is essential for semicircular canal formation in zebrafish inner ear

We have analyzed the functional role of neuronal calcium sensor‐1 (Ncs‐1) in zebrafish development. We identified two orthologs of the mammalian NCS‐1 gene. Full‐length cDNAs encoding zebrafish Ncs‐1a and Ncs‐1b polypeptides were cloned and characterized. Whole‐mount in situ hybridization revealed t...

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Veröffentlicht in:	Journal of neurobiology 2005-09, Vol.64 (3), p.285-297
Hauptverfasser:	Blasiole, Brian, Kabbani, Nadine, Boehmler, Wendy, Thisse, Bernard, Thisse, Christine, Canfield, Victor, Levenson, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biochemistry, Molecular Biology Blotting, Western Brain Brain - embryology Calcium-Binding Proteins Calcium-Binding Proteins - genetics Cloning, Molecular ear development Freshwater Gene Expression Regulation, Developmental Humans In Situ Hybridization Life Sciences Molecular biology Molecular Sequence Data morpholinos neuronal calcium sensor Neuronal Calcium-Sensor Proteins Neuropeptides Neuropeptides - genetics Oligonucleotides, Antisense Phylogeny Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger RNA, Messenger - analysis Semicircular Canals Semicircular Canals - embryology Sequence Homology, Amino Acid Zebrafish Zebrafish Proteins Zebrafish Proteins - genetics
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