The histone H3.3 chaperone HIRA is essential for chromatin assembly in the male pronucleus

In sexually reproducing animals, a crucial step in zygote formation is the decondensation of the fertilizing sperm nucleus into a DNA replication-competent male pronucleus. Genome-wide nucleosome assembly on paternal DNA implies the replacement of sperm chromosomal proteins, such as protamines, by m...

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Veröffentlicht in:	Nature (London) 2005-10, Vol.437 (7063), p.1386-1390
Hauptverfasser:	Loppin, Benjamin, Bonnefoy, Emilie, Anselme, Caroline, Laurençon, Anne, Karr, Timothy L., Couble, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Cell Cycle Proteins Cell Cycle Proteins - chemistry Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Nucleus Cell Nucleus - genetics Cell Nucleus - metabolism Chromatin Chromatin - chemistry Chromatin - genetics Chromatin - metabolism Chromatin. Chromosome Chromosomes Deoxyribonucleic acid DNA DNA Replication Drosophila melanogaster Drosophila melanogaster - cytology Drosophila melanogaster - genetics Drosophila Proteins Drosophila Proteins - chemistry Drosophila Proteins - genetics Drosophila Proteins - metabolism Female Fertilization Fundamental and applied biological sciences. Psychology Genetics Genomics Histone Chaperones Histones Histones - classification Histones - genetics Histones - metabolism Humanities and Social Sciences letter Life Sciences Male Methylation Molecular and cellular biology Molecular genetics Molecular Sequence Data multidisciplinary Mutation Mutation - genetics Ovum Ovum - cytology Proteins Science Science (multidisciplinary) Spermatozoa Spermatozoa - cytology Transcription Factors Transcription Factors - chemistry Transcription Factors - genetics Transcription Factors - metabolism
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