A GATA/RUNX cis-regulatory module couples Drosophila blood cell commitment and differentiation into crystal cells

Members of the RUNX and GATA transcription factor families play critical roles during hematopoiesis from Drosophila to mammals. In Drosophila, the formation of the crystal cell hematopoietic lineage depends on the continuous expression of the lineage-specific RUNX factor Lozenge (Lz) and on its inte...

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Veröffentlicht in:	Developmental biology 2007-05, Vol.305 (2), p.726-734
Hauptverfasser:	Ferjoux, Géraldine, Augé, Benoit, Boyer, Karène, Haenlin, Marc, Waltzer, Lucas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry, Molecular Biology Catechol Oxidase Catechol Oxidase - genetics Cell Differentiation Cell Differentiation - physiology Conserved Sequence Core Binding Factor alpha Subunits Core Binding Factor alpha Subunits - physiology DNA-Binding Proteins DNA-Binding Proteins - metabolism DNA-Binding Proteins - physiology Drosophila Drosophila melanogaster Drosophila melanogaster - cytology Drosophila melanogaster - embryology Drosophila melanogaster - enzymology Drosophila melanogaster - growth & development Drosophila Proteins Drosophila Proteins - metabolism Drosophila Proteins - physiology Enzyme Precursors Enzyme Precursors - genetics GATA GATA Transcription Factors GATA Transcription Factors - metabolism GATA Transcription Factors - physiology Gene Expression Regulation, Developmental Gene Expression Regulation, Developmental - physiology Hematopoiesis Hemocytes Hemocytes - cytology Larva Larva - cytology Larva - growth & development Life Sciences RUNX Transcription Transcription Factors Transcription Factors - metabolism Transcription Factors - physiology
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