A Biogenetically Based Strategy Towards the Polycyclic Core Skeleton of Sarain A

An approach to the polycyclic core of sarain A, based upon a proposed biogenetic route, is presented. Condensation of a protected amino acid with a bromoacrylamide and subsequent addition of malonaldehyde sodium salt and methyl iodide afforded, after stereoselective hydrogenation, a highly functiona...

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Veröffentlicht in:	European Journal of Organic Chemistry 2006-09, Vol.2006 (18), p.4106-4114
Hauptverfasser:	Ge, Cheng Sheng, Hourcade, Stéphane, Ferdenzi, Antoine, Chiaroni, Angèle, Mons, Stéphane, Delpech, Bernard, Marazano, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids Biomimetic synthesis Chemical Sciences Multicomponent synthesis Organic chemistry Pyrrolidines Reduction Sarain A
Online-Zugang:	Volltext
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