Neurogenic pain and steroid synthesis in the spinal cord

The spinal cord (SC) is a biosynthetic center for neurosteroids, including pregnenolone (PREG), progesterone (PROG), and 3alpha/5alpha-tetrahydroprogesterone (3alpha/5alpha-THP). In particular, an active form of cytochrome P450 sidechain cleavage (P450scc) has been localized in sensory networks of t...

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Veröffentlicht in:	Journal of molecular neuroscience 2006, Vol.28 (1), p.17-32
Hauptverfasser:	Patte-Mensah, Christine, Kibaly, Cherkaouia, Boudard, Domitille, Schaeffer, Véronique, Béglé, Aurélie, Saredi, Simona, Meyer, Laurence, Mensah-Nyagan, Ayikoe G
Format:	Artikel
Sprache:	eng
Schlagworte:	3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - metabolism 3-Hydroxysteroid Dehydrogenases - metabolism 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism Animals Biosynthesis Cholesterol Side-Chain Cleavage Enzyme - metabolism Enzymes Humans Life Sciences Ligation Neurons - cytology Neurons - metabolism Neurons and Cognition Pain - metabolism Pregnenolone - metabolism Progesterone - analogs & derivatives Progesterone - metabolism Rodents Sciatic Nerve - surgery Spinal Cord - cytology Spinal Cord - metabolism Steroid 17-alpha-Hydroxylase - metabolism Steroids - biosynthesis
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