Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2

Expression of the full set of human and mouse groups I, II, V, X, and XII secreted phospholipases A 2 (sPLA 2 s) in Escherichia coli and insect cells has provided pure recombinant enzymes for detailed comparative interfacial kinetic and binding studies. The set of mammalian sPLA 2 s display dramatic...

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Veröffentlicht in:	The Journal of biological chemistry 2002-12, Vol.277 (50), p.48535-48549
Hauptverfasser:	Singer, Alan G, Ghomashchi, Farideh, Le Calvez, Catherine, Bollinger, James, Bezzine, Sofiane, Rouault, Morgane, Sadilek, Martin, Nguyen, Eric, Lazdunski, Michel, Lambeau, Gerard, Gelb, Michael H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acids - metabolism Dithiothreitol - pharmacology Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Humans Kinetics Mice Molecular Structure Phospholipases A - antagonists & inhibitors Phospholipases A - metabolism Protein Binding Recombinant Proteins - antagonists & inhibitors Recombinant Proteins - metabolism
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