Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer

We investigated the expression levels of human lactoferrin (Lf), a steroid hormone‐inducible gene product the expression of which is often altered during oncogenesis, and of Δ‐lactoferrin (ΔLf), its alternative isoform, which has been shown to be absent from tumor cell lines in commonly used human b...

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Veröffentlicht in:	International journal of cancer 2005-03, Vol.114 (2), p.299-306
Hauptverfasser:	Benaïssa, Monique, Peyrat, Jean‐Philippe, Hornez, Louis, Mariller, Christophe, Mazurier, Joël, Pierce, Annick
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biochemistry, Molecular Biology Biological and medical sciences breast cancer Breast Neoplasms Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - pathology Cell Line, Tumor DNA Primers Female Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Humans Lactoferrin Lactoferrin - genetics Life Sciences mammary gland Mammary gland diseases Medical sciences overall survival Prognosis prognostic value Protein Isoforms Protein Isoforms - genetics relapse‐free survival Retrospective Studies Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger RNA, Messenger - genetics Survival Analysis Time Factors Tumors Δ‐lactoferrin
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