Indicanine A, a New 3-Phenylcoumarin from Root Bark of Erythrina indica
A new 3-phenylcoumarin, indicanine A (1), has been isolated from the root bark of the African medicinal plant Erythrina indica, together with three known compounds, robustic acid (2), daidzein, and 8-prenyldaidzein. The structure of the new compound was characterized, as 4-hydroxy-5-methoxy-3-(4‘-me...
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| Veröffentlicht in: | Journal of natural products (Washington, D.C.) D.C.), 2000-06, Vol.63 (6), p.855-856 |
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| container_issue | 6 |
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| container_title | Journal of natural products (Washington, D.C.) |
| container_volume | 63 |
| creator | Nkengfack, Augustin E Waffo, Alain K Azebaze, Guy A Fomum, Zacharias T Meyer, Michele Bodo, Bernard van Heerden, Fanie R |
| description | A new 3-phenylcoumarin, indicanine A (1), has been isolated from the root bark of the African medicinal plant Erythrina indica, together with three known compounds, robustic acid (2), daidzein, and 8-prenyldaidzein. The structure of the new compound was characterized, as 4-hydroxy-5-methoxy-3-(4‘-methoxyphenyl)-2‘ ‘-(1-methylethenyl)dihydrofurano[4‘ ‘,5‘ ‘:6,7]coumarin by means of extensive spectroscopic analyses. The compounds were found to be devoid of in vitro antibacterial activity. |
| doi_str_mv | 10.1021/np990300y |
| format | Article |
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The structure of the new compound was characterized, as 4-hydroxy-5-methoxy-3-(4‘-methoxyphenyl)-2‘ ‘-(1-methylethenyl)dihydrofurano[4‘ ‘,5‘ ‘:6,7]coumarin by means of extensive spectroscopic analyses. The compounds were found to be devoid of in vitro antibacterial activity.</description><identifier>ISSN: 0163-3864</identifier><identifier>EISSN: 1520-6025</identifier><identifier>DOI: 10.1021/np990300y</identifier><identifier>PMID: 10869220</identifier><identifier>CODEN: JNPRDF</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Biochemistry ; Biochemistry, Molecular Biology ; Biological and medical sciences ; Coumarins - chemistry ; Coumarins - isolation & purification ; Coumarins - pharmacology ; Erythrina - chemistry ; Escherichia coli - drug effects ; General pharmacology ; Isoflavones - chemistry ; Isoflavones - isolation & purification ; Isoflavones - pharmacology ; Life Sciences ; Medical sciences ; Microbial Sensitivity Tests ; Mycobacterium - drug effects ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Plant Roots - chemistry ; Plants, Medicinal ; Staphylococcus aureus - drug effects</subject><ispartof>Journal of natural products (Washington, D.C.), 2000-06, Vol.63 (6), p.855-856</ispartof><rights>Copyright © 2000 American Chemical Society and American Society of Pharmacognosy</rights><rights>2000 INIST-CNRS</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a412t-4dca7e82d93e7b904440151f0ef7c8a06d14ad10cf7e037af468a9453915b5d63</citedby><cites>FETCH-LOGICAL-a412t-4dca7e82d93e7b904440151f0ef7c8a06d14ad10cf7e037af468a9453915b5d63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/np990300y$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/np990300y$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>230,314,780,784,885,2765,27076,27924,27925,56738,56788</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1426600$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10869220$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00086737$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Nkengfack, Augustin E</creatorcontrib><creatorcontrib>Waffo, Alain K</creatorcontrib><creatorcontrib>Azebaze, Guy A</creatorcontrib><creatorcontrib>Fomum, Zacharias T</creatorcontrib><creatorcontrib>Meyer, Michele</creatorcontrib><creatorcontrib>Bodo, Bernard</creatorcontrib><creatorcontrib>van Heerden, Fanie R</creatorcontrib><title>Indicanine A, a New 3-Phenylcoumarin from Root Bark of Erythrina indica</title><title>Journal of natural products (Washington, D.C.)</title><addtitle>J. Nat. Prod</addtitle><description>A new 3-phenylcoumarin, indicanine A (1), has been isolated from the root bark of the African medicinal plant Erythrina indica, together with three known compounds, robustic acid (2), daidzein, and 8-prenyldaidzein. The structure of the new compound was characterized, as 4-hydroxy-5-methoxy-3-(4‘-methoxyphenyl)-2‘ ‘-(1-methylethenyl)dihydrofurano[4‘ ‘,5‘ ‘:6,7]coumarin by means of extensive spectroscopic analyses. The compounds were found to be devoid of in vitro antibacterial activity.</description><subject>Biochemistry</subject><subject>Biochemistry, Molecular Biology</subject><subject>Biological and medical sciences</subject><subject>Coumarins - chemistry</subject><subject>Coumarins - isolation & purification</subject><subject>Coumarins - pharmacology</subject><subject>Erythrina - chemistry</subject><subject>Escherichia coli - drug effects</subject><subject>General pharmacology</subject><subject>Isoflavones - chemistry</subject><subject>Isoflavones - isolation & purification</subject><subject>Isoflavones - pharmacology</subject><subject>Life Sciences</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Mycobacterium - drug effects</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Plant Roots - chemistry</subject><subject>Plants, Medicinal</subject><subject>Staphylococcus aureus - drug effects</subject><issn>0163-3864</issn><issn>1520-6025</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0F1v0zAUBmALgVgZXPAHkC9gEhKB488kl101uk3VmEbh1jp1HDUjjYudAP33uKTquNiVpXMevTp-CXnN4CMDzj5127IEAbB7QiZMccg0cPWUTIBpkYlCyxPyIsZ7gIRK9ZycMCh0yTlMyPyqqxqLXdM5Ov1Akd6431Rkt2vX7Vrrhw2GpqN18Bt6531PzzH8oL6mF2HXr9MKafMv4CV5VmMb3avDe0q-fb5Yzi6zxZf51Wy6yFAy3meyspi7glelcPmqBCklMMVqcHVuCwRdMYkVA1vnDkSOtdQFllKJkqmVqrQ4Je_H3DW2ZhuadN_OeGzM5XRh9rP0yULnIv_Fkj0b7Tb4n4OLvdk00bq2xc75IZqccSYVlw-hNvgYg6uPyQzMvmFzbDjZN4fQYbVx1X9yrDSBtweA0WJbB-xsEx-c5FrDnmUja2Lv_hzXqV6zP1-Z5e1XI27urr_P5kujkn83erTR3PshdKnmR-77Czaxmt8</recordid><startdate>20000601</startdate><enddate>20000601</enddate><creator>Nkengfack, Augustin E</creator><creator>Waffo, Alain K</creator><creator>Azebaze, Guy A</creator><creator>Fomum, Zacharias T</creator><creator>Meyer, Michele</creator><creator>Bodo, Bernard</creator><creator>van Heerden, Fanie R</creator><general>American Chemical Society</general><general>American Society of Pharmacognosy</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>20000601</creationdate><title>Indicanine A, a New 3-Phenylcoumarin from Root Bark of Erythrina indica</title><author>Nkengfack, Augustin E ; Waffo, Alain K ; Azebaze, Guy A ; Fomum, Zacharias T ; Meyer, Michele ; Bodo, Bernard ; van Heerden, Fanie R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a412t-4dca7e82d93e7b904440151f0ef7c8a06d14ad10cf7e037af468a9453915b5d63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Biochemistry</topic><topic>Biochemistry, Molecular Biology</topic><topic>Biological and medical sciences</topic><topic>Coumarins - chemistry</topic><topic>Coumarins - isolation & purification</topic><topic>Coumarins - pharmacology</topic><topic>Erythrina - chemistry</topic><topic>Escherichia coli - drug effects</topic><topic>General pharmacology</topic><topic>Isoflavones - chemistry</topic><topic>Isoflavones - isolation & purification</topic><topic>Isoflavones - pharmacology</topic><topic>Life Sciences</topic><topic>Medical sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Mycobacterium - drug effects</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Plant Roots - chemistry</topic><topic>Plants, Medicinal</topic><topic>Staphylococcus aureus - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nkengfack, Augustin E</creatorcontrib><creatorcontrib>Waffo, Alain K</creatorcontrib><creatorcontrib>Azebaze, Guy A</creatorcontrib><creatorcontrib>Fomum, Zacharias T</creatorcontrib><creatorcontrib>Meyer, Michele</creatorcontrib><creatorcontrib>Bodo, Bernard</creatorcontrib><creatorcontrib>van Heerden, Fanie R</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Journal of natural products (Washington, D.C.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nkengfack, Augustin E</au><au>Waffo, Alain K</au><au>Azebaze, Guy A</au><au>Fomum, Zacharias T</au><au>Meyer, Michele</au><au>Bodo, Bernard</au><au>van Heerden, Fanie R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Indicanine A, a New 3-Phenylcoumarin from Root Bark of Erythrina indica</atitle><jtitle>Journal of natural products (Washington, D.C.)</jtitle><addtitle>J. Nat. Prod</addtitle><date>2000-06-01</date><risdate>2000</risdate><volume>63</volume><issue>6</issue><spage>855</spage><epage>856</epage><pages>855-856</pages><issn>0163-3864</issn><eissn>1520-6025</eissn><coden>JNPRDF</coden><abstract>A new 3-phenylcoumarin, indicanine A (1), has been isolated from the root bark of the African medicinal plant Erythrina indica, together with three known compounds, robustic acid (2), daidzein, and 8-prenyldaidzein. The structure of the new compound was characterized, as 4-hydroxy-5-methoxy-3-(4‘-methoxyphenyl)-2‘ ‘-(1-methylethenyl)dihydrofurano[4‘ ‘,5‘ ‘:6,7]coumarin by means of extensive spectroscopic analyses. The compounds were found to be devoid of in vitro antibacterial activity.</abstract><cop>Washington, DC</cop><cop>Glendale, AZ</cop><pub>American Chemical Society</pub><pmid>10869220</pmid><doi>10.1021/np990300y</doi><tpages>2</tpages></addata></record> |
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| ispartof | Journal of natural products (Washington, D.C.), 2000-06, Vol.63 (6), p.855-856 |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Biochemistry Biochemistry, Molecular Biology Biological and medical sciences Coumarins - chemistry Coumarins - isolation & purification Coumarins - pharmacology Erythrina - chemistry Escherichia coli - drug effects General pharmacology Isoflavones - chemistry Isoflavones - isolation & purification Isoflavones - pharmacology Life Sciences Medical sciences Microbial Sensitivity Tests Mycobacterium - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Roots - chemistry Plants, Medicinal Staphylococcus aureus - drug effects |
| title | Indicanine A, a New 3-Phenylcoumarin from Root Bark of Erythrina indica |
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