Use of functionalized aromatic organozinc reagents in the three-component Mannich-type synthesis of diarylmethylamines

Efficient syntheses of functionalized diarylmethylamines have been realized according to a one-step three-component coupling between an aromatic aldehyde, a secondary amine and an aromatic organozinc reagent. Phenyl rings can be substituted by functional groups and either aromatic or non-aromatic am...

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Veröffentlicht in:	Tetrahedron letters 2006-04, Vol.47 (15), p.2497-2500
Hauptverfasser:	Le Gall, Erwan, Troupel, Michel, Nédélec, Jean-Yves
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic aldehydes Aromatic organozinc reagents Diarylmethylamines Secondary amines Three-component reaction
Online-Zugang:	Volltext
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