An Essential Cytoplasmic Function for the Nuclear Poly(A) Binding Protein, PABP2, in Poly(A) Tail Length Control and Early Development in Drosophila

Translational control of maternal mRNA through regulation of poly(A) tail length is crucial during early development. The nuclear poly(A) binding protein, PABP2, was identified biochemically from its role in nuclear polyadenylation. Here, we analyze the in vivo function of PABP2 in Drosophila. PABP2...

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Veröffentlicht in:	Developmental cell 2005-10, Vol.9 (4), p.511-522
Hauptverfasser:	Benoit, Béatrice, Mitou, Géraldine, Chartier, Aymeric, Temme, Claudia, Zaessinger, Sophie, Wahle, Elmar, Busseau, Isabelle, Simonelig, Martine
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biochemistry Biochemistry, Molecular Biology Biological and medical sciences Body Patterning Cell Cycle - physiology Cell differentiation, maturation, development, hematopoiesis Cell physiology Cyclin B - genetics Cyclin B - metabolism Drosophila melanogaster - embryology Drosophila Proteins - genetics Drosophila Proteins - metabolism Embryo, Nonmammalian - anatomy & histology Embryo, Nonmammalian - physiology Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Life Sciences Male Molecular and cellular biology Molecular Sequence Data Oocytes - physiology Other Poly(A)-Binding Protein II - genetics Poly(A)-Binding Protein II - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Ribonucleases - genetics Ribonucleases - metabolism RNA, Messenger - metabolism
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