Genomic organization of amplified MYC genes suggests distinct mechanisms of amplification in tumorigenesis

Integration of the human papillomavirus (HPV) genome into the host genome is associated with the disruption of the HPV E2 gene and with amplification and rearrangement of the viral and flanking cellular sequences. Molecular characterization of the genomic structures of coamplified HPV sequences and...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2005-02, Vol.65 (4), p.1174-1179
Hauptverfasser:	HERRICK, John, CONTI, Chiara, TEISSIER, Sebastien, THIERRY, Francoise, COUTURIER, Jérome, SASTRE-GARAU, Xavier, FAVRE, Michel, ORTH, Gérard, BENSIMON, Aaron
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Cancer Cellular Biology Female Gene Amplification Genes, myc Genes, myc - genetics Genome, Human Human papillomavirus Humans Life Sciences Medical sciences Multigene Family Oncogene Proteins, Viral Oncogene Proteins, Viral - genetics Papillomaviridae Papillomaviridae - genetics Pharmacology. Drug treatments Subcellular Processes Uterine Cervical Neoplasms Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - virology Virus Integration Virus Integration - genetics
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