RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans

Atherosclerosis involves angiogenesis and inflammation with the ability of endothelial cells and monocytes to respond to chemokines. We addressed here by in vitro and in vivo approaches, the role of the chemokine Regulated on Activation, Normal T Cell Expressed and Secreted (RANTES)/CCL5 on angiogen...

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Veröffentlicht in:	Angiogenesis (London) 2012-12, Vol.15 (4), p.727-744
Hauptverfasser:	Suffee, N., Hlawaty, H., Meddahi-Pelle, A., Maillard, L., Louedec, L., Haddad, O., Martin, L., Laguillier, C., Richard, B., Oudar, O., Letourneur, D., Charnaux, N., Sutton, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biochemistry, Molecular Biology Biological and medical sciences Biomedical and Life Sciences Biomedicine Blood and lymphatic vessels Cancer Cancer Research Cardiology Cardiology. Vascular system Cardiovascular system Cell Biology Chemical Sciences Chemokine CCL5 - physiology Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Enzyme-Linked Immunosorbent Assay Glycosaminoglycans - physiology Immunohistochemistry Life Sciences Male Medical sciences Medicinal Chemistry Neovascularization, Physiologic - physiology Oncology Ophthalmology Original Paper Pharmacology. Drug treatments Rats Rats, Wistar Receptors, CCR1 - physiology Vasodilator agents. Cerebral vasodilators
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