Transcriptomic Studies Suggest a Coincident Role for Apoptosis and Pyroptosis but Not for Autophagic Neuronal Death in TBEV-Infected Human Neuronal/Glial Cells

Tick-borne encephalitis virus (TBEV), a member of the Flaviviridae family, Flavivirus genus, is responsible for neurological symptoms that may cause permanent disability or death. With an incidence on the rise, it is the major arbovirus affecting humans in Central/Northern Europe and North-Eastern A...

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Veröffentlicht in:	Viruses 2021-11, Vol.13 (11), p.2255, Article 2255
Hauptverfasser:	Fares, Mazigh, Gorna, Kamila, Berry, Noemie, Cochet-Bernoin, Marielle, Piumi, Francois, Blanchet, Odile, Haddad, Nadia, Richardson, Jennifer, Coulpier, Muriel
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - genetics Arachnids Astrocytes - metabolism Autophagy Brain Cell death Cell differentiation central nervous system Communication Encephalitis Encephalitis Viruses, Tick-Borne Encephalitis Viruses, Tick-Borne - pathogenicity Fetuses flavivirus Gene regulation Genes Glial cells Human health and pathology Humans Infections Infectious diseases Life Sciences Life Sciences & Biomedicine Molecular modelling Nervous system Neural stem cells Neurobiology Neuroglia - metabolism Neuroglia - pathology Neuroglia - virology neuronal death Neuronal-glial interactions Neurons - metabolism Neurons - pathology Neurons - virology Neurons and Cognition pathological modeling Progenitor cells Pyroptosis Pyroptosis - genetics Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics Science & Technology Software Tick-borne encephalitis tick-borne encephalitis virus TNF family members TNF-Related Apoptosis-Inducing Ligand - genetics Transcriptome Transcriptomics Viral infections Virology West Nile virus
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