First-in-human immunoPET imaging of HIV-1 infection using 89 Zr-labeled VRC01 broadly neutralizing antibody

A major obstacle to achieving long-term antiretroviral (ART) free remission or functional cure of HIV infection is the presence of persistently infected cells that establish a long-lived viral reservoir. HIV largely resides in anatomical regions that are inaccessible to routine sampling, however, an...

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Hauptverfasser: Beckford-Vera, DR, Flavell, RR, Seo, Y, Martinez-Ortiz, E, Aslam, M, Thanh, C, Fehrman, E, Pardons, Marion, Kumar, S, Deitchman, AN, Ravanfar, V, Schulte, B, Wu, IK, Pan, T, Reeves, JD, Nixon, CC, Iyer, NS, Torres, L, Munter, SE, Hyunh, T, Petropoulos, CJ, Hoh, R, Franc, BL, Gama, L, Koup, RA, Mascola, JR, Chomont, N, Deeks, SG, VanBrocklin, HF, Henrich, TJ
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Sprache:eng
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