A large retrospective assessment of voriconazole exposure in patients treated with extracorporeal membrane oxygenation

Background: Voriconazole is one of the first-line therapies for invasive pulmonary aspergillosis. Drug concentrations might be significantly influenced by the use of extracorporeal membrane oxygenation (ECMO). We aimed to assess the effect of ECMO on voriconazole exposure in a large patient populati...

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Hauptverfasser:	Van Daele, Ruth, Bekkers, Britt, Lindfors, Mattias, Broman, Lars Mikael, Schauwvlieghe, Alexander, Rijnders, Bart, Hunfeld, Nicole G. M, Juffermans, Nicole P, Taccone, Fabio Silvio, Sousa, Carlos Antonio Coimbra, Jacquet, Luc-Marie, Laterre, Pierre-Francois, Nulens, Eric, Grootaert, Veerle, Lyster, Haifa, Reed, Anna, Patel, Brijesh, Meersseman, Philippe, Debaveye, Yves, Wauters, Joost, Vandenbriele, Christophe, Spriet, Isabel
Format:	Artikel
Sprache:	eng
Schlagworte:	ANTIFUNGAL AGENTS CASPOFUNGIN CRITICALLY-ILL PATIENTS exposure extracorporeal membrane GUIDELINES INFECTIOUS-DISEASES INVASIVE ASPERGILLOSIS invasive fungal infections Medicine and Health Sciences oxygenation PHARMACOKINETICS PLASMA-CONCENTRATIONS POSACONAZOLE SEQUESTRATION therapeutic drug monitoring variability voriconazole
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