GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A

Dendritic cells (DC) initiate the adaptive immune response. Glucocorticoids (GCs) down-modulate the function of DC. Compound A (CpdA, (2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride) is a plant-derived GR-ligand with marked dissociative properties. We investigated the effects of CpdA o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Barcala Tabarrozzi, Andres E, Andreone, Luz, Deckers, Julie, Castro, Carla N, Gimeno, María L, Ariolfo, Laura, Berguer, Paula M, Antunica-Noguerol, María, Liberman, Ana C, Vettorazzi, Sabine, Tuckermann, Jan P, De Bosscher, Karolien, Perone, Marcelo J
Format:	Artikel
Sprache:	eng
Schlagworte:	ANTIGEN PRESENTATION Biology and Life Sciences DIFFERENTIATION INDUCED APOPTOSIS INDUCED ARTHRITIS MATURATION MOUSE MODEL NF-KAPPA-B PLANT-ORIGIN REGULATORY T-CELLS TRANSCRIPTION FACTORS
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!