Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans

For cells the passage from life to death can involve a regulated, programmed transition. In contrast to cell death, the mechanisms of systemic collapse underlying organismal death remain poorly understood. Here we present evidence of a cascade of cell death involving the calpain-cathepsin necrosis p...

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Hauptverfasser:	Coburn, Cassandra, Allman, Erik, Mahanti, Parag, Benedetto, Alexandre, Cabreiro, Filipe, Pincus, Zachary, Matthijssens, Filip, Araiz, Caroline, Mandel, Abraham, Vlachos, Manolis, Edwards, Sally-Anne, Fischer, Grahame, Davidson, Alexander, Pryor, Rosina E, Stevens, Ailsa, Slack, Frank J, Tavernarakis, Nektarios, Braeckman, Bart, Schroeder, Frank C, Nehrke, Keith, Gems, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology and Life Sciences ENDOPLASMIC-RETICULUM GAP-JUNCTIONS GENETIC-ANALYSIS IN-VIVO LIFE-SPAN NEMATODE CAENORHABDITIS-ELEGANS NEURONAL DEATH OXIDATIVE STRESS PROGRAMMED CELL-DEATH RHYTHMIC BEHAVIOR
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