The miR-17-92 MicroRNA Cluster regulates multiple components of the TGF-beta Pathway in neuroblastoma

The miR-17-92 microRNA cluster is often activated in cancer cells, but the identity of its targets remains elusive. Using SILAC and quantitative mass spectrometry, we examined the effects of activation of the miR-17-92 cluster on global protein expression in neuroblastoma (NB) cells. Our results rev...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Mestdagh, Pieter, Bostrom, Anna-Karin, Impens, Francis, Fredlund, Erik, Van Peer, Gert, De Antonellis, Pasqualino, von Stedingk, Kristoffer, Ghesquière, Bart, Schulte, Stefanie, Dews, Michael, Thomas-Tikhonenko, Andrei, Schulte, Johannes H, Zollo, Massimo, Schramm, Alexander, Gevaert, Kris, Axelson, Hakan, Speleman, Franki, Vandesompele, Jo
Format:	Artikel
Sprache:	eng
Schlagworte:	BIOGENESIS Biology and Life Sciences CANCER EXPRESSION GENE TARGETS GROWTH INDUCTION MALIGNANT PHENOTYPE NEURONAL DIFFERENTIATION PROLIFERATION PROTEOMICS
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!