MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation

Correlative evidence has suggested that the methyl-CpG-binding protein MeCP2 contributes to the formation of heterochromatin condensates via liquid-liquid phase separation. This interpretation has been reinforced by the observation that heterochromatin, DNA methylation and MeCP2 co-localise within p...

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Bibliographische Detailangaben

Hauptverfasser:	Pantier, Raphael, Brown, Megan, Han, Sicheng, Paton, Katie, Meek, Stephen, Montavon, Thomas, Shukeir, Nicholas, Mchugh, Toni, Kelly, David A, Hochepied, Tino, Libert, Claude, Jenuwein, Thomas, Burdon, Tom, Bird, Adrian
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology and Life Sciences CHROMOSOMAL LOCALIZATION DOMAIN DYNAMICS EVOLUTION Medicine and Health Sciences MUTATIONS NEURONS PROTEIN RETT-SYNDROME SATELLITE DNA SEQUENCE
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