Understanding the nebulisation of antibiotics : the key role of lung microdialysis studies

BackgroundNebulisation of antibiotics is a promising treatment for ventilator-associated pneumonia (VAP) caused by multidrug-resistant organisms. Ensuring effective antibiotic concentrations at the site of infection in the interstitial space fluid is crucial for clinical outcomes. Current assessment...

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Hauptverfasser:	Dhanani, Jayesh, Roberts, Jason A, Monsel, Antoine, Torres, Antoni, Kollef, Marin, Rouby, Jean-Jacques, Arvaniti, Kostoula, Assefi, Mona, Bassetti, Matteo, Blot, Stijn, Boisson, Matthieu, Bouglé, Adrien, Constantin, Jean-Michel, Dimopoulos, George, Dugernier, Jonathan, Dureau, Pauline, Felton, Timothy, Koutsoukou, Antonia, Kyriakoudi, Anna, Laterre, Pierre-François, Leone, Marc, Lepère, Victoria, Bassi, Gianluigi Li, Liao, Xuelian, Mimoz, Olivier, Nair, Girish B, Niederman, Michael, Palmer, Lucy B, Pelosi, Paolo, Pereira, Jose Manuel, Pontikis, Konstantinos, Poulakou, Garyphalia, Pugin, Jérôme, Qian, Chuanyun, Qu, Jie-ming, Rello, Jordi, Roberts, Jason, Routsi, Christina, Smaldone, Gerald C, Türkoğlu, Melda, Welte, Tobias, Wolff, Michel, Jing, Xia, Yang, Li, Yang, Ting, Zhu, Ying-gang, the European Investigators Network for Nebulized Antibiotics in Ventilator-associated Pneumonia, [missing]
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic nebulisation Critical Care and Intensive Care Medicine Epithelial lining fluid Lung microdialysis Medicine and Health Sciences Nebulised aminoglycosides Nebulised polymyxins Ventilator-associated pneumonia
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