Hemothorax and retroperitoneal hematoma after anticoagulation with enoxaparin

A 58-year-old woman with chronic obstructive pulmonary disease had spontaneous bilateral hemothorax and a retroperitoneal hematoma after 4 days of anticoagulation therapy with enoxaparin (1 mg/kg subcutaneously every 12 hours) for suspected pulmonary thromboembolism. The patient was successfully man...

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Veröffentlicht in:Southern medical journal (Birmingham, Ala.) Ala.), 2002-08, Vol.95 (8), p.936-938
Hauptverfasser: MRUG, Michal, MISHRA, Prashant V, LUSANE, Henry C, CUNNINGHAM, J. Martin, ALPERT, Martin A
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container_issue 8
container_start_page 936
container_title Southern medical journal (Birmingham, Ala.)
container_volume 95
creator MRUG, Michal
MISHRA, Prashant V
LUSANE, Henry C
CUNNINGHAM, J. Martin
ALPERT, Martin A
description A 58-year-old woman with chronic obstructive pulmonary disease had spontaneous bilateral hemothorax and a retroperitoneal hematoma after 4 days of anticoagulation therapy with enoxaparin (1 mg/kg subcutaneously every 12 hours) for suspected pulmonary thromboembolism. The patient was successfully managed with red blood cell and plasma transfusions, multiple thoracenteses for evacuation of blood from the pleural space, short-term mechanical ventilation, and administration of bronchodilators, corticosteroids, and antibiotics. This is the first report of spontaneous hemothorax and the third report of spontaneous retroperitoneal hematoma associated with enoxaparin therapy.
doi_str_mv 10.1097/00007611-200208000-00031
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source MEDLINE; Journals@Ovid Complete
subjects Anticoagulants (Medicine)
Anticoagulants - adverse effects
Anticoagulants - therapeutic use
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Care and treatment
Complications and side effects
Drug toxicity and drugs side effects treatment
Enoxaparin
Enoxaparin - adverse effects
Enoxaparin - therapeutic use
Female
Hematoma
Hematoma - chemically induced
Hematoma - diagnostic imaging
Hematoma - pathology
Hemothorax - chemically induced
Hemothorax - diagnostic imaging
Hemothorax - pathology
Humans
Lung diseases, Obstructive
Medical sciences
Middle Aged
Miscellaneous (drug allergy, mutagens, teratogens...)
Pharmacology. Drug treatments
Physiological aspects
Pulmonary Embolism - drug therapy
Radiography
Retroperitoneal Space - diagnostic imaging
Retroperitoneal Space - pathology
Thromboembolism
title Hemothorax and retroperitoneal hematoma after anticoagulation with enoxaparin
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