A flexible loop in the paxillin LIM3 domain mediates its direct binding to integrin [beta] subunits

Integrins are fundamental for cell adhesion and the formation of focal adhesions (FA). Accordingly, these receptors guide embryonic development, tissue maintenance, and haemostasis but are also involved in cancer invasion and metastasis. A detailed understanding of the molecular interactions that dr...

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Veröffentlicht in:	PLoS biology 2024-09, Vol.22 (9)
Hauptverfasser:	Baade, Timo, Michaelis, Marcus, Prestel, Andreas, Paone, Christoph, Klishin, Nikolai, Herbinger, Marleen, Scheinost, Laura, Nedielkov, Ruslan, Hauck, Christof R, Möller, Heiko M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell adhesion Integrins Physiological aspects Zinc finger proteins
Online-Zugang:	Volltext
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