Synthesis, characterization, preliminary molecular docking, pharmacological activity, and ADME studies of some new pyrazoline derivatives as anti-breast cancer agents

This work studied the anti-breast cancer activities of pyrazoline-containing benzenesulfonamides (6–10) in vitro and silico. The GOLD suite performed molecular docking on the target human estrogen receptor and the PARPA1 antagonist crystal structure, yielding comparable results using tamoxifen as a...

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Veröffentlicht in:	Farmacija 2024-09, Vol.71 (11), p.1-10
Hauptverfasser:	Fadhil, Hayder R, Raauf, Ayad M. R, Mahdi, Monther F
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cancer Crystals Drug therapy Estrogen Oncology, Experimental Structure Tamoxifen
Online-Zugang:	Volltext
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