An Uncommon Case of Pediatric Nasopharyngeal Carcinoma with Bone Metastases and Enchondromas Evaluated Using PET/CT
Nowadays, the utility of positron emission tomography/computed tomography (PET/CT) is well established in nasopharyngeal carcinoma (NPC). The incidence of NPC in the West population, especially in children, is very low. We present the first Italian case of a pediatric patient with NPC followed up wi...
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Veröffentlicht in: | Molecular imaging and radionuclide therapy 2024-06, Vol.33 (2), p.121 |
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description | Nowadays, the utility of positron emission tomography/computed tomography (PET/CT) is well established in nasopharyngeal carcinoma (NPC). The incidence of NPC in the West population, especially in children, is very low. We present the first Italian case of a pediatric patient with NPC followed up with ([.sup.18)F-fluorodeoxyglucose] ( ([.sup.18F-FDG])) PET/CT scan in addition to the standard follow-up imaging methods, including CT and magnetic resonance imaging. The ([.sup.18F-FDG]) PET/CT scan was helpful in discriminating between metastatic and benign osseous lesions, thereby helping clinicians to determine the most appropriate therapeutic regimen. These findings support the clinical utility of ([.sup.18F-FDG]) PET/CT in the diagnostic work-up of pediatric patients with NPC. Keywords: Positron emission tomography, ([.sup.18)F-fluorodeoxyglucose], nasopharyngeal carcinoma, pediatrics Gunumuzde nazofaringeal karsinomda (NFK) pozitron emisyon tomografisi/bilgisayarli tomografinin (PET/BT) kullanimi iyice yerlesmistir. Bati populasyonunda, ozellikle de pediatrik yasta NFK'nin gorulme sikligi cok dusuktur. BT ve manyetik rezonans goruntuleme dahil olmak uzere standart takip goruntuleme yontemlerine ek olarak ([.sup.18)F-florodeoksiglukoz] ( ([.sup.18F-FDG])) PET/BT taramasi yoluyla takip edilen NFK'li ilk Italyan pediatrik hastayi sunuyoruz. ([.sup.18F-FDG]) PET/BT taramasi, metastatik ve iyi huylu kemik lezyonlari arasinda ayrim yapilmasinda ve klinisyenlerin en uygun terapotik rejimi belirlemesine yardimci olmustur. Bu bulgular, NFK'li pediatrik hastalarin tanisal calismalarinda ([.sup.18F-FDG]) PET/BT taramasinin klinik faydasini desteklemektedir. Anahtar kelimeler: Pozitron emisyon tomografisi, ([.sup.18)F-florodeoksiglukoz], nazofaringeal karsinom, pediatri |
doi_str_mv | 10.4274/mirt.galenos.2023.69672 |
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The incidence of NPC in the West population, especially in children, is very low. We present the first Italian case of a pediatric patient with NPC followed up with ([.sup.18)F-fluorodeoxyglucose] ( ([.sup.18F-FDG])) PET/CT scan in addition to the standard follow-up imaging methods, including CT and magnetic resonance imaging. The ([.sup.18F-FDG]) PET/CT scan was helpful in discriminating between metastatic and benign osseous lesions, thereby helping clinicians to determine the most appropriate therapeutic regimen. These findings support the clinical utility of ([.sup.18F-FDG]) PET/CT in the diagnostic work-up of pediatric patients with NPC. Keywords: Positron emission tomography, ([.sup.18)F-fluorodeoxyglucose], nasopharyngeal carcinoma, pediatrics Gunumuzde nazofaringeal karsinomda (NFK) pozitron emisyon tomografisi/bilgisayarli tomografinin (PET/BT) kullanimi iyice yerlesmistir. Bati populasyonunda, ozellikle de pediatrik yasta NFK'nin gorulme sikligi cok dusuktur. BT ve manyetik rezonans goruntuleme dahil olmak uzere standart takip goruntuleme yontemlerine ek olarak ([.sup.18)F-florodeoksiglukoz] ( ([.sup.18F-FDG])) PET/BT taramasi yoluyla takip edilen NFK'li ilk Italyan pediatrik hastayi sunuyoruz. ([.sup.18F-FDG]) PET/BT taramasi, metastatik ve iyi huylu kemik lezyonlari arasinda ayrim yapilmasinda ve klinisyenlerin en uygun terapotik rejimi belirlemesine yardimci olmustur. Bu bulgular, NFK'li pediatrik hastalarin tanisal calismalarinda ([.sup.18F-FDG]) PET/BT taramasinin klinik faydasini desteklemektedir. Anahtar kelimeler: Pozitron emisyon tomografisi, ([.sup.18)F-florodeoksiglukoz], nazofaringeal karsinom, pediatri</description><identifier>ISSN: 2146-1414</identifier><identifier>DOI: 10.4274/mirt.galenos.2023.69672</identifier><language>eng</language><publisher>Galenos Yayinevi Tic. Ltd</publisher><subject>Cancer in children ; CT imaging ; Diagnosis ; Methods ; Nasopharyngeal cancer ; PET imaging</subject><ispartof>Molecular imaging and radionuclide therapy, 2024-06, Vol.33 (2), p.121</ispartof><rights>COPYRIGHT 2024 Galenos Yayinevi Tic. 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The incidence of NPC in the West population, especially in children, is very low. We present the first Italian case of a pediatric patient with NPC followed up with ([.sup.18)F-fluorodeoxyglucose] ( ([.sup.18F-FDG])) PET/CT scan in addition to the standard follow-up imaging methods, including CT and magnetic resonance imaging. The ([.sup.18F-FDG]) PET/CT scan was helpful in discriminating between metastatic and benign osseous lesions, thereby helping clinicians to determine the most appropriate therapeutic regimen. These findings support the clinical utility of ([.sup.18F-FDG]) PET/CT in the diagnostic work-up of pediatric patients with NPC. Keywords: Positron emission tomography, ([.sup.18)F-fluorodeoxyglucose], nasopharyngeal carcinoma, pediatrics Gunumuzde nazofaringeal karsinomda (NFK) pozitron emisyon tomografisi/bilgisayarli tomografinin (PET/BT) kullanimi iyice yerlesmistir. Bati populasyonunda, ozellikle de pediatrik yasta NFK'nin gorulme sikligi cok dusuktur. BT ve manyetik rezonans goruntuleme dahil olmak uzere standart takip goruntuleme yontemlerine ek olarak ([.sup.18)F-florodeoksiglukoz] ( ([.sup.18F-FDG])) PET/BT taramasi yoluyla takip edilen NFK'li ilk Italyan pediatrik hastayi sunuyoruz. ([.sup.18F-FDG]) PET/BT taramasi, metastatik ve iyi huylu kemik lezyonlari arasinda ayrim yapilmasinda ve klinisyenlerin en uygun terapotik rejimi belirlemesine yardimci olmustur. Bu bulgular, NFK'li pediatrik hastalarin tanisal calismalarinda ([.sup.18F-FDG]) PET/BT taramasinin klinik faydasini desteklemektedir. Anahtar kelimeler: Pozitron emisyon tomografisi, ([.sup.18)F-florodeoksiglukoz], nazofaringeal karsinom, pediatri</description><subject>Cancer in children</subject><subject>CT imaging</subject><subject>Diagnosis</subject><subject>Methods</subject><subject>Nasopharyngeal cancer</subject><subject>PET imaging</subject><issn>2146-1414</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptkE1PwzAMhnMAiWnsNxCJc7s0SZPmOKrxIQ3YoTtPbpp0QW2CmgLi3xMEBw74tWTZel5LNkJXBck5lXw9umnOexiMDzGnhLJcKCHpGVrQgous4AW_QKsYX0iKigpSVQsUNx4fvA7jGDyuIRocLN6bzsE8OY2fIIbXE0yfvjcwJGDSzocR8IebT_gmeIMfzQwxpYkYfIe3Xp-C76YERbx9h-ENZtPhQ3S-x_tts66bS3RuYYhm9VuXqLndNvV9tnu-e6g3u6wXUmWsVFrLTipJLZVWUV1YolrGCslKIXjJGasMJRpsa4kFLQFSL9sSKtVSxZbo-mft90-OztswT6BHF_VxUxFWcS7IN5X_QyV1ZnQ6HWhdmv8xfAG3gm52</recordid><startdate>20240601</startdate><enddate>20240601</enddate><creator>Quartuccio, Natale</creator><creator>Ialuna, Salvatore</creator><creator>Poma, Salvatore</creator><creator>Lentini, Vincenzo Luca</creator><creator>Pitruzzella, Alessandro</creator><creator>Galfano, Giuseppe Mario</creator><creator>Moreci, Antonino Maria</creator><creator>Modica, Domenico Michele</creator><general>Galenos Yayinevi Tic. Ltd</general><scope/></search><sort><creationdate>20240601</creationdate><title>An Uncommon Case of Pediatric Nasopharyngeal Carcinoma with Bone Metastases and Enchondromas Evaluated Using PET/CT</title><author>Quartuccio, Natale ; Ialuna, Salvatore ; Poma, Salvatore ; Lentini, Vincenzo Luca ; Pitruzzella, Alessandro ; Galfano, Giuseppe Mario ; Moreci, Antonino Maria ; Modica, Domenico Michele</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g679-359cc7d7972f27f92c1f09b33173566454338e20cafbf0fac7aa8e27b5a89b293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Cancer in children</topic><topic>CT imaging</topic><topic>Diagnosis</topic><topic>Methods</topic><topic>Nasopharyngeal cancer</topic><topic>PET imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Quartuccio, Natale</creatorcontrib><creatorcontrib>Ialuna, Salvatore</creatorcontrib><creatorcontrib>Poma, Salvatore</creatorcontrib><creatorcontrib>Lentini, Vincenzo Luca</creatorcontrib><creatorcontrib>Pitruzzella, Alessandro</creatorcontrib><creatorcontrib>Galfano, Giuseppe Mario</creatorcontrib><creatorcontrib>Moreci, Antonino Maria</creatorcontrib><creatorcontrib>Modica, Domenico Michele</creatorcontrib><jtitle>Molecular imaging and radionuclide therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Quartuccio, Natale</au><au>Ialuna, Salvatore</au><au>Poma, Salvatore</au><au>Lentini, Vincenzo Luca</au><au>Pitruzzella, Alessandro</au><au>Galfano, Giuseppe Mario</au><au>Moreci, Antonino Maria</au><au>Modica, Domenico Michele</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Uncommon Case of Pediatric Nasopharyngeal Carcinoma with Bone Metastases and Enchondromas Evaluated Using PET/CT</atitle><jtitle>Molecular imaging and radionuclide therapy</jtitle><date>2024-06-01</date><risdate>2024</risdate><volume>33</volume><issue>2</issue><spage>121</spage><pages>121-</pages><issn>2146-1414</issn><abstract>Nowadays, the utility of positron emission tomography/computed tomography (PET/CT) is well established in nasopharyngeal carcinoma (NPC). The incidence of NPC in the West population, especially in children, is very low. We present the first Italian case of a pediatric patient with NPC followed up with ([.sup.18)F-fluorodeoxyglucose] ( ([.sup.18F-FDG])) PET/CT scan in addition to the standard follow-up imaging methods, including CT and magnetic resonance imaging. The ([.sup.18F-FDG]) PET/CT scan was helpful in discriminating between metastatic and benign osseous lesions, thereby helping clinicians to determine the most appropriate therapeutic regimen. These findings support the clinical utility of ([.sup.18F-FDG]) PET/CT in the diagnostic work-up of pediatric patients with NPC. Keywords: Positron emission tomography, ([.sup.18)F-fluorodeoxyglucose], nasopharyngeal carcinoma, pediatrics Gunumuzde nazofaringeal karsinomda (NFK) pozitron emisyon tomografisi/bilgisayarli tomografinin (PET/BT) kullanimi iyice yerlesmistir. Bati populasyonunda, ozellikle de pediatrik yasta NFK'nin gorulme sikligi cok dusuktur. BT ve manyetik rezonans goruntuleme dahil olmak uzere standart takip goruntuleme yontemlerine ek olarak ([.sup.18)F-florodeoksiglukoz] ( ([.sup.18F-FDG])) PET/BT taramasi yoluyla takip edilen NFK'li ilk Italyan pediatrik hastayi sunuyoruz. ([.sup.18F-FDG]) PET/BT taramasi, metastatik ve iyi huylu kemik lezyonlari arasinda ayrim yapilmasinda ve klinisyenlerin en uygun terapotik rejimi belirlemesine yardimci olmustur. Bu bulgular, NFK'li pediatrik hastalarin tanisal calismalarinda ([.sup.18F-FDG]) PET/BT taramasinin klinik faydasini desteklemektedir. Anahtar kelimeler: Pozitron emisyon tomografisi, ([.sup.18)F-florodeoksiglukoz], nazofaringeal karsinom, pediatri</abstract><pub>Galenos Yayinevi Tic. Ltd</pub><doi>10.4274/mirt.galenos.2023.69672</doi></addata></record> |
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subjects | Cancer in children CT imaging Diagnosis Methods Nasopharyngeal cancer PET imaging |
title | An Uncommon Case of Pediatric Nasopharyngeal Carcinoma with Bone Metastases and Enchondromas Evaluated Using PET/CT |
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