F]Flotaza for Aβ Plaque Diagnostic Imaging: Evaluation in Postmortem Human Alzheimer’s Disease Brain Hippocampus and PET/CT Imaging in 5xFAD Transgenic Mice

The diagnostic value of imaging Aβ plaques in Alzheimer’s disease (AD) has accelerated the development of fluorine-18 labeled radiotracers with a longer half-life for easier translation to clinical use. We have developed [[sup.18]F]flotaza, which shows high binding to Aβ plaques in postmortem human...

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Veröffentlicht in:	International journal of molecular sciences 2024-07, Vol.25 (14)
Hauptverfasser:	Sandhu, Yasmin K, Bath, Harman S, Shergill, Jasmine, Liang, Christopher, Syed, Amina U, Ngo, Allyson, Karim, Fariha, Serrano, Geidy E, Beach, Thomas G, Mukherjee, Jogeshwar
Format:	Artikel
Sprache:	eng
Schlagworte:	Advertising executives Alzheimer's disease Arizona Brain Diseases Genetic engineering PET imaging
Online-Zugang:	Volltext
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