IGFBP2 induces podocyte apoptosis promoted by mitochondrial damage via integrin [alpha]5/FAK in diabetic kidney disease

Podocyte apoptosis or loss is the pivotal pathological characteristic of diabetic kidney disease (DKD). Insulin-like growth factor-binding protein 2 (IGFBP2) have a proinflammatory and proapoptotic effect on diseases. Previous studies have shown that serum IGFBP2 level significantly increased in DKD...

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Veröffentlicht in:	Apoptosis (London) 2024-08, Vol.29 (7-8), p.1109
Hauptverfasser:	Wang, Xiaochen, Zhang, Yifan, Chi, Kun, Ji, Yuwei, Zhang, Keying, Li, Ping, Fu, Zhangning
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Dextrose Diseases Glucose Integrins Kidney diseases Medical research Medicine, Experimental Protein binding Type 2 diabetes
Online-Zugang:	Volltext
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