Inhibition and reversal of a TGF-[beta]1 induced myofibroblast phenotype by adipose tissue-derived paracrine factors

Background Hypertrophic scarring results from myofibroblast differentiation and persistence during wound healing. Currently no effective treatment for hypertrophic scarring exists however, autologous fat grafting has been shown to improve scar elasticity, appearance, and function. The aim of this st...

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Veröffentlicht in:	Stem cell research & therapy 2024-06, Vol.15 (1)
Hauptverfasser:	Higginbotham, S, Workman, V. L, Giblin, A-V, Green, N. H, Lambert, D. W, Hearnden, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissues Bone morphogenetic proteins Care and treatment Ethylenediaminetetraacetic acid Genetic aspects Pharmaceutical industry Scientific equipment and supplies industry Transforming growth factors Wounds and injuries
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