Influence of Lipopolysaccharide-Interacting Peptides Fusion with Endolysin LysECD7 and Fatty Acid Derivatization on the Efficacy against IAcinetobacter baumannii/I Infection In Vitro and In Vivo

Acinetobacter baumannii has developed multiple drug resistances, posing a significant threat to antibiotic efficacy. LysECD7, an endolysin derived from phages, could be a promising therapeutic agent against multi-drug resistance A. baumannii. In this study, in order to further enhance the antibacter...

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Veröffentlicht in:	Viruses 2024-05, Vol.16 (5)
Hauptverfasser:	Li, Xiaowan, Shangguan, Wenwen, Yang, Xiaoqian, Hu, Xiaoyue, Li, Yanan, Zhao, Wenjie, Feng, Meiqing, Feng, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Antibiotics Bacteria Drug resistance in microorganisms Ethylenediaminetetraacetic acid Fatty acids Health aspects Infection Peptides
Online-Zugang:	Volltext
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