Research Progress in Pharmacological Effects and Mechanisms of IAngelica sinensis/I against Cardiovascular and Cerebrovascular Diseases
Angelica sinensis (Oliv.) Diels (A. sinensis) is a medicinal and edible values substance, which could promote blood circulation and enrich blood. It possesses rich chemical components and nutrients, which have significant therapeutic effects on cardiovascular and cerebrovascular diseases. It is comm...
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| Veröffentlicht in: | Molecules (Basel, Switzerland) Switzerland), 2024-05, Vol.29 (9) |
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| container_title | Molecules (Basel, Switzerland) |
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| creator | Chen, Linlin Fan, Bei Wang, Fengzhong Song, Yang Wang, Xizhi Meng, Ying Chen, Yumin Xia, Qing Sun, Jing |
| description | Angelica sinensis (Oliv.) Diels (A. sinensis) is a medicinal and edible values substance, which could promote blood circulation and enrich blood. It possesses rich chemical components and nutrients, which have significant therapeutic effects on cardiovascular and cerebrovascular diseases. It is commonly used for the prevention and treatment of cardiovascular and cerebrovascular diseases in the elderly, especially in improving ischemic damage to the heart and brain, protecting vascular cells, and regulating inflammatory reactions. This article reviews the main pharmacological effects and clinical research of A. sinensis on cardiovascular and cerebrovascular diseases in recent years, explores the effect of its chemical components on cardiovascular and cerebrovascular diseases by regulating the expression of functional proteins and inhibiting inflammation, anti-apoptosis, and antioxidant mechanisms. It provides a reference for further research on A. sinensis and the development of related drugs. It provides a new reference direction for the in-depth research and application of A. sinensis in the prevention, improvement, and treatment of cardiovascular and cerebrovascular diseases. |
| doi_str_mv | 10.3390/molecules29092100 |
| format | Article |
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Diels (A. sinensis) is a medicinal and edible values substance, which could promote blood circulation and enrich blood. It possesses rich chemical components and nutrients, which have significant therapeutic effects on cardiovascular and cerebrovascular diseases. It is commonly used for the prevention and treatment of cardiovascular and cerebrovascular diseases in the elderly, especially in improving ischemic damage to the heart and brain, protecting vascular cells, and regulating inflammatory reactions. This article reviews the main pharmacological effects and clinical research of A. sinensis on cardiovascular and cerebrovascular diseases in recent years, explores the effect of its chemical components on cardiovascular and cerebrovascular diseases by regulating the expression of functional proteins and inhibiting inflammation, anti-apoptosis, and antioxidant mechanisms. It provides a reference for further research on A. sinensis and the development of related drugs. 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Diels (A. sinensis) is a medicinal and edible values substance, which could promote blood circulation and enrich blood. It possesses rich chemical components and nutrients, which have significant therapeutic effects on cardiovascular and cerebrovascular diseases. It is commonly used for the prevention and treatment of cardiovascular and cerebrovascular diseases in the elderly, especially in improving ischemic damage to the heart and brain, protecting vascular cells, and regulating inflammatory reactions. This article reviews the main pharmacological effects and clinical research of A. sinensis on cardiovascular and cerebrovascular diseases in recent years, explores the effect of its chemical components on cardiovascular and cerebrovascular diseases by regulating the expression of functional proteins and inhibiting inflammation, anti-apoptosis, and antioxidant mechanisms. It provides a reference for further research on A. sinensis and the development of related drugs. It provides a new reference direction for the in-depth research and application of A. sinensis in the prevention, improvement, and treatment of cardiovascular and cerebrovascular diseases.</description><subject>Aged</subject><subject>Antioxidants</subject><subject>Brain damage</subject><subject>Health aspects</subject><subject>Inflammation</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Proteins</subject><issn>1420-3049</issn><issn>1420-3049</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptjk9LAzEQxYMoWKsfwFvA87bZJNtsjmWtWqhYpPeSP5NtZDcLmepX8Gu7qGAPMocZHr_33hByW7KZEJrN-6ED994Bcs00Lxk7I5NSclYIJvX5yX1JrhDfGOOlLKsJ-XwFBJPdgW7z0GZApDHR7cHk3rihG9roTEdXIYA7IjXJ02dwB5Mi9kiHQNfL1EI3QhRjgoQR52tqWhMTHmljso_Dh8HxM5O_3Q1ksPlPu49jPQJek4tgOoSb3z0lu4fVrnkqNi-P62a5KdqFYoUP0nrluJXKV46FRa09qxlnlnsupa-VFZI5q731lRa2ktxZpYLQVe1dJcSU3P3EtqaDfUxhOGbj-ohuv1RaVKqsSzZSs3-ocTz00Q0JQhz1E8MXvrl2-Q</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Chen, Linlin</creator><creator>Fan, Bei</creator><creator>Wang, Fengzhong</creator><creator>Song, Yang</creator><creator>Wang, Xizhi</creator><creator>Meng, Ying</creator><creator>Chen, Yumin</creator><creator>Xia, Qing</creator><creator>Sun, Jing</creator><general>MDPI AG</general><scope/></search><sort><creationdate>20240501</creationdate><title>Research Progress in Pharmacological Effects and Mechanisms of IAngelica sinensis/I against Cardiovascular and Cerebrovascular Diseases</title><author>Chen, Linlin ; Fan, Bei ; Wang, Fengzhong ; Song, Yang ; Wang, Xizhi ; Meng, Ying ; Chen, Yumin ; Xia, Qing ; Sun, Jing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g670-df4bd7c2b47d5c0f689d08020b2d244d87b340cb9dbd593b542cb77f3958dc533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>Antioxidants</topic><topic>Brain damage</topic><topic>Health aspects</topic><topic>Inflammation</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Proteins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Linlin</creatorcontrib><creatorcontrib>Fan, Bei</creatorcontrib><creatorcontrib>Wang, Fengzhong</creatorcontrib><creatorcontrib>Song, Yang</creatorcontrib><creatorcontrib>Wang, Xizhi</creatorcontrib><creatorcontrib>Meng, Ying</creatorcontrib><creatorcontrib>Chen, Yumin</creatorcontrib><creatorcontrib>Xia, Qing</creatorcontrib><creatorcontrib>Sun, Jing</creatorcontrib><jtitle>Molecules (Basel, Switzerland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Linlin</au><au>Fan, Bei</au><au>Wang, Fengzhong</au><au>Song, Yang</au><au>Wang, Xizhi</au><au>Meng, Ying</au><au>Chen, Yumin</au><au>Xia, Qing</au><au>Sun, Jing</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Research Progress in Pharmacological Effects and Mechanisms of IAngelica sinensis/I against Cardiovascular and Cerebrovascular Diseases</atitle><jtitle>Molecules (Basel, Switzerland)</jtitle><date>2024-05-01</date><risdate>2024</risdate><volume>29</volume><issue>9</issue><issn>1420-3049</issn><eissn>1420-3049</eissn><abstract>Angelica sinensis (Oliv.) Diels (A. sinensis) is a medicinal and edible values substance, which could promote blood circulation and enrich blood. It possesses rich chemical components and nutrients, which have significant therapeutic effects on cardiovascular and cerebrovascular diseases. It is commonly used for the prevention and treatment of cardiovascular and cerebrovascular diseases in the elderly, especially in improving ischemic damage to the heart and brain, protecting vascular cells, and regulating inflammatory reactions. This article reviews the main pharmacological effects and clinical research of A. sinensis on cardiovascular and cerebrovascular diseases in recent years, explores the effect of its chemical components on cardiovascular and cerebrovascular diseases by regulating the expression of functional proteins and inhibiting inflammation, anti-apoptosis, and antioxidant mechanisms. It provides a reference for further research on A. sinensis and the development of related drugs. It provides a new reference direction for the in-depth research and application of A. sinensis in the prevention, improvement, and treatment of cardiovascular and cerebrovascular diseases.</abstract><pub>MDPI AG</pub><doi>10.3390/molecules29092100</doi></addata></record> |
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| source | DOAJ Directory of Open Access Journals; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Aged Antioxidants Brain damage Health aspects Inflammation Medical research Medicine, Experimental Proteins |
| title | Research Progress in Pharmacological Effects and Mechanisms of IAngelica sinensis/I against Cardiovascular and Cerebrovascular Diseases |
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