Randomly Methylated Iβ/I-Cyclodextrin Inclusion Complex with Ketoconazole: Preparation, Characterization, and Improvement of Pharmacological Profiles

As a powerful imidazole antifungal drug, ketoconazole’s low solubility (0.017 mg/mL), together with its odor and irritation, limited its clinical applications. The inclusion complex of ketoconazole with randomly methylated β-cyclodextrin was prepared by using an aqueous solution method after cyclode...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2024-05, Vol.29 (9)
Hauptverfasser:	Ding, Yili, Xu, Shufeng, Ding, Charles, Zhang, Zhiyuan, Xu, Zhe
Format:	Artikel
Sprache:	eng
Schlagworte:	Ketoconazole
Online-Zugang:	Volltext
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