Synapsin E-domain is essential for [alpha]-synuclein function

The cytosolic proteins synucleins and synapsins are thought to play cooperative roles in regulating synaptic vesicle (SV) recycling, but mechanistic insight is lacking. Here, we identify the synapsin E-domain as an essential functional binding-partner of [alpha]-synuclein ([alpha]-syn). Synapsin E-d...

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Veröffentlicht in:	eLife 2024-05, Vol.12
Hauptverfasser:	Stavsky, Alexandra, Parra-Rivas, Leonardo A, Tal, Shani, Riba, Jen, Madhivanan, Kayalvizhi, Roy, Subhojit, Gitler, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Nervous system diseases Neurons Photographic industry Proteins Scientific equipment and supplies industry
Online-Zugang:	Volltext
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