Agonist-Induced Ca[sup.2+] Signaling in HEK-293-Derived Cells Expressing a Single IP[sub.3] Receptor Isoform

In mammals, three genes encode IP[sub.3] receptors (IP[sub.3] Rs), which are involved in agonist-induced Ca[sup.2+] signaling in cells of apparently all types. Using the CRISPR/Cas9 approach for disruption of two out of three IP[sub.3] R genes in HEK-293 cells, we generated three monoclonal cell lin...

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Veröffentlicht in:	Cells (Basel, Switzerland) Switzerland), 2024-04, Vol.13 (7)
Hauptverfasser:	Kochkina, Ekaterina N, Kopylova, Elizaveta E, Rogachevskaja, Olga A, Kovalenko, Nina P, Kabanova, Natalia V, Kotova, Polina D, Bystrova, Marina F, Kolesnikov, Stanislav S
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Genetic vectors Permeability
Online-Zugang:	Volltext
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