Adenosine Increases the Immunosuppressive Capacity of Cervical Cancer Cells by Increasing PD-L1 Expression and TGF-β Production through Its Interaction with A[sub.2A]R/A[sub.2B]R

The present study provides evidence showing that adenosine (Ado) increases the expression of programmed death ligand 1 (PD-L1) in cervical cancer (CeCa) cells by interacting with A[sub.2A] R/A[sub.2B] R and that TGF-β1 acts in an autocrine manner to induce PD-L1 expression, enhancing the immunosuppr...

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Veröffentlicht in:	Pharmaceuticals (Basel, Switzerland) Switzerland), 2024-03, Vol.17 (3)
Hauptverfasser:	García-Rocha, Rosario, Monroy-García, Alberto, Vázquez-Cruz, Ana Luisa, Marín-Aquino, Luis Antonio, Weiss-Steider, Benny, Hernández-Montes, Jorge, Don-López, Christian Azucena, Molina-Castillo, Gabriela, Mora-García, María de Lourdes
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Cancer Care and treatment Cell receptors Cervical cancer Development and progression Genetic aspects Health aspects Immune response Immunosuppression Membrane proteins Oncology, Experimental Transforming growth factors
Online-Zugang:	Volltext
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