The Discovery of Novel Agents against IStaphylococcus aureus/I by Targeting Sortase A: A Combination of Virtual Screening and Experimental Validation

Staphylococcus aureus (S. aureus), commonly known as “superbugs”, is a highly pathogenic bacterium that poses a serious threat to human health. There is an urgent need to replace traditional antibiotics with novel drugs to combat S. aureus. Sortase A (SrtA) is a crucial transpeptidase involved in th...

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