An Overview of One Health Concept Focusing on Toxoplasmosis/Tek Saglik Konseptinde Toxoplasmosis'e Genel Bir Bakis

The "One Health" concept is a universal approach to sustainably balancing and optimizing the health of humans, animals, and ecosystems. This approach is based on the health of humans, domestic and wild animals, and plants in a wider environment in which self-renewable ecosystems exist, wit...

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Veröffentlicht in:Türkiye parazitolojii dergisi 2023-12, Vol.47 (4), p.256
Hauptverfasser: Inci, Abdullah, Sohel, Mahmodul Hasan, Babür, Cahit, Uslu, Sadullah, Karademir, Gupse Kübra, Yürük, Merve, Düzlü, Önder, Kizgin, Alina Denis, Yildirim, Alparslan
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container_start_page 256
container_title Türkiye parazitolojii dergisi
container_volume 47
creator Inci, Abdullah
Sohel, Mahmodul Hasan
Babür, Cahit
Uslu, Sadullah
Karademir, Gupse Kübra
Yürük, Merve
Düzlü, Önder
Kizgin, Alina Denis
Yildirim, Alparslan
description The "One Health" concept is a universal approach to sustainably balancing and optimizing the health of humans, animals, and ecosystems. This approach is based on the health of humans, domestic and wild animals, and plants in a wider environment in which self-renewable ecosystems exist, with essential characteristics of integration, unifying and holistic perspective. Toxoplasmosis, one of the most common zoonotic infections in both terrestrial and oceanic ecosystems in the world, is an ideal model disease for the "One Health" approach. Toxoplasmosis is a zoonotic disease caused by the obligate intracellular pathogen protozoan Toxoplasma gondii. In the life cycle of T. gondii, the definitive host is domestic cats and felines, and the intermediate hosts are all mammals (including humans), birds and reptiles. The infected cats have primary importance and play a crucial role in the contamination of habitats in the ecosystems with T. gondii oocysts. Thus, ecosystems with domestic cats and stray cats are contaminated with cat feces infected with T. gondii oocytes. T. gondii positivity has been scientifically demonstrated in all warm-blooded animals in terrestrial and aquatic habitats. The disease causes deaths and abortions in farm animals, resulting in great economic losses. However, the disease causes great problems in humans, especially pregnant women. During pregnancy, it may have effects such as congenital infections, lesions in the eye and brain of the fetus, premature birth, intrauterine growth retardation, fever, pneumonia, thrombocytopenia, ocular lesions, encephalitis, and abortion. The mechanism of death and abortion of the fetus in a pregnant woman infected with T. gondii occurs as a result of complete disruption of the maternal immune mechanism. The struggle against toxoplasmosis requires the universal collaboration and coordination of the World Organization for Animal Health, the World Health Organization and the World Food Organization in the "One Health" concept and integrative approaches of all responsible disciplines. Establishing universal environmental safety with the prevention and control of toxoplasmosis requires the annihilation of the feces of the infected cats using suitable techniques firstly. Then routinely, the monitoring and treatment of T. gondii positivity in cats, avoiding contact with contaminated foods and materials, and development of modern treatment and vaccine options. Particularly, mandatory monitoring or screening of T. go
doi_str_mv 10.4274/tpd.galenos.2023.38039
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This approach is based on the health of humans, domestic and wild animals, and plants in a wider environment in which self-renewable ecosystems exist, with essential characteristics of integration, unifying and holistic perspective. Toxoplasmosis, one of the most common zoonotic infections in both terrestrial and oceanic ecosystems in the world, is an ideal model disease for the "One Health" approach. Toxoplasmosis is a zoonotic disease caused by the obligate intracellular pathogen protozoan Toxoplasma gondii. In the life cycle of T. gondii, the definitive host is domestic cats and felines, and the intermediate hosts are all mammals (including humans), birds and reptiles. The infected cats have primary importance and play a crucial role in the contamination of habitats in the ecosystems with T. gondii oocysts. Thus, ecosystems with domestic cats and stray cats are contaminated with cat feces infected with T. gondii oocytes. T. gondii positivity has been scientifically demonstrated in all warm-blooded animals in terrestrial and aquatic habitats. The disease causes deaths and abortions in farm animals, resulting in great economic losses. However, the disease causes great problems in humans, especially pregnant women. During pregnancy, it may have effects such as congenital infections, lesions in the eye and brain of the fetus, premature birth, intrauterine growth retardation, fever, pneumonia, thrombocytopenia, ocular lesions, encephalitis, and abortion. The mechanism of death and abortion of the fetus in a pregnant woman infected with T. gondii occurs as a result of complete disruption of the maternal immune mechanism. The struggle against toxoplasmosis requires the universal collaboration and coordination of the World Organization for Animal Health, the World Health Organization and the World Food Organization in the "One Health" concept and integrative approaches of all responsible disciplines. Establishing universal environmental safety with the prevention and control of toxoplasmosis requires the annihilation of the feces of the infected cats using suitable techniques firstly. Then routinely, the monitoring and treatment of T. gondii positivity in cats, avoiding contact with contaminated foods and materials, and development of modern treatment and vaccine options. Particularly, mandatory monitoring or screening of T. gondii positivity during the pregnancy period in humans should be done. It would be beneficial to replace the French model, especially in the monitoring of disease in humans. In this article, the ecology of toxoplasmosis was reviewed at the base of the "One Health" concept. Keywords: One health, ecology of toxoplasmosis, Toxoplasma gondii, pregnancy, prevention and control, interdisciplinary, struggle "Tek Saglik" konsepti, insanlarin, hayvanlarin ve ekosistemlerin sagligini sürdürülebilir bir sekilde dengelemeyi ve optimize etmeyi esas alan üniversal bir yaklasimdir. Bu yaklasim entegresyon, birlestirici ve holostik temel karakteristikleri ile insanlarin, evcil ve vahsi hayvanlarin, bitkilerin ve içerisinde kendi kendini yenileyebilir ekosistemlerin bulundugu daha genis bir çevrenin sagligini esas alir. Dünyada hem karasal hem de okyanus ekosistemlerinde en yaygin zoonotik karakterli enfeksiyonlardan birisi olan Toxoplasmosis, "Tek Saglik" konsepti için ideal model bir hastaliktir. Toxoplasmosis, zoonotik karakterli, zorunlu hücre içi patojen protozoon Toxoplasma gondii'nin meydana getirdigi bir hastaliktir. Hastalik etkeni T gondii 'nin hayat siklusunda son konagi evcil kedi ve kedigiller, ara konaklari ise insan dahil tüm memeliler, kanatli hayvanlar ve reptillerdir. Hastalik etkeni patojen T gondii 'nin hayat siklusunda kediler hem son konak hem de ara konak vazifesi gördükleri için, ekosistemin kontaminasyonundan da primer öneme sahiptirler. Dolayisiyla evcil kedilerin ve serbest dolasan kedilerin bulundugu ekosistemler, T gondii oocytleriyle enfekte kedi diskilariyla kontamine olurlar. Toxoplasma gondii pozitifligi, karasal ve sucul habitatlarda tüm sicakkanlilarda bilimsel çalismalarla gösterilmistir. Hastalik çiftlik hayvanlarinda ölümlere ve abortlara yol açarak büyük ekonomik kayiplar olusturur. Bununla beraber hastalik, insanlarda özellikle hamile kadinlarda büyük problemlere neden olmaktadir. Gebelikte T gondii konjenital enfeksiyonlari, fetüsün göz ve beyninde lezyonlar, prematüre dogum, intrauterin büyüme geriligi, ates, pnömoni, trombositopeni, oküler lezyonlar, ensefalit ve abort gibi patolojik bozukluklara yol açar. Toxoplasma gondii ile enfekte bir gebede ölüm ve abort, maternal bagisiklik mekanizmasinin tamamen bozulmasi sonucu sekillenmektedir. Toxoplasmosis'e karsi mücadele, üniversal boyutta Dünya Hayvan Sagligi Teskilati, Dünya Saglik Teskilati ve Dünya Gida Teskilati'nin "Tek Saglik" konseptinde koordinasyonunu ve tüm paydas ülkelerde ulusal düzeyde ilgili tüm disiplinlerin bütünlestirici yaklasimlarini gerektirir. Bu baglamda özellikle hastaliktan korunma ve kontrolde, teknigine uygun olarak çevre güvenligi için kedi diskisinin imhasi, kedilerde pozitifligin izlenmesi ve tedavisi, kontamine gida ve malzemelerle temastan kaçinmak, modern tedavi ve asi seçeneklerinin gelistirilmesi ve insan ve hayvanlarda hastaligin zorunlu izlenmesi/taramasi gerekmektedir. Özellikle insanlarda hastaligin izlenmesinde Fransa modeline geçilmesinde yarar vardir. Bu makalede, "Tek Saglik" konseptinde toxoplasmosis'in ekolojisi incelenmistir. Anahtar Kelimeler: Tek saglik, toxoplasmosisin ekolojisi, Toxoplasma gondii, gebelik, korunma ve kontrol, disiplinlerarasi, mücadele</description><identifier>ISSN: 1300-6320</identifier><identifier>DOI: 10.4274/tpd.galenos.2023.38039</identifier><language>eng</language><publisher>Galenos Yayinevi Tic. Ltd</publisher><subject>Abortion ; Analysis ; Cats ; Ecology ; Food contamination ; Health aspects ; Pregnant women ; Prevention ; Toxoplasmosis ; World health ; Zoonoses</subject><ispartof>Türkiye parazitolojii dergisi, 2023-12, Vol.47 (4), p.256</ispartof><rights>COPYRIGHT 2023 Galenos Yayinevi Tic. Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27924,27925</link.rule.ids></links><search><creatorcontrib>Inci, Abdullah</creatorcontrib><creatorcontrib>Sohel, Mahmodul Hasan</creatorcontrib><creatorcontrib>Babür, Cahit</creatorcontrib><creatorcontrib>Uslu, Sadullah</creatorcontrib><creatorcontrib>Karademir, Gupse Kübra</creatorcontrib><creatorcontrib>Yürük, Merve</creatorcontrib><creatorcontrib>Düzlü, Önder</creatorcontrib><creatorcontrib>Kizgin, Alina Denis</creatorcontrib><creatorcontrib>Yildirim, Alparslan</creatorcontrib><title>An Overview of One Health Concept Focusing on Toxoplasmosis/Tek Saglik Konseptinde Toxoplasmosis'e Genel Bir Bakis</title><title>Türkiye parazitolojii dergisi</title><description>The "One Health" concept is a universal approach to sustainably balancing and optimizing the health of humans, animals, and ecosystems. This approach is based on the health of humans, domestic and wild animals, and plants in a wider environment in which self-renewable ecosystems exist, with essential characteristics of integration, unifying and holistic perspective. Toxoplasmosis, one of the most common zoonotic infections in both terrestrial and oceanic ecosystems in the world, is an ideal model disease for the "One Health" approach. Toxoplasmosis is a zoonotic disease caused by the obligate intracellular pathogen protozoan Toxoplasma gondii. In the life cycle of T. gondii, the definitive host is domestic cats and felines, and the intermediate hosts are all mammals (including humans), birds and reptiles. The infected cats have primary importance and play a crucial role in the contamination of habitats in the ecosystems with T. gondii oocysts. Thus, ecosystems with domestic cats and stray cats are contaminated with cat feces infected with T. gondii oocytes. T. gondii positivity has been scientifically demonstrated in all warm-blooded animals in terrestrial and aquatic habitats. The disease causes deaths and abortions in farm animals, resulting in great economic losses. However, the disease causes great problems in humans, especially pregnant women. During pregnancy, it may have effects such as congenital infections, lesions in the eye and brain of the fetus, premature birth, intrauterine growth retardation, fever, pneumonia, thrombocytopenia, ocular lesions, encephalitis, and abortion. The mechanism of death and abortion of the fetus in a pregnant woman infected with T. gondii occurs as a result of complete disruption of the maternal immune mechanism. The struggle against toxoplasmosis requires the universal collaboration and coordination of the World Organization for Animal Health, the World Health Organization and the World Food Organization in the "One Health" concept and integrative approaches of all responsible disciplines. Establishing universal environmental safety with the prevention and control of toxoplasmosis requires the annihilation of the feces of the infected cats using suitable techniques firstly. Then routinely, the monitoring and treatment of T. gondii positivity in cats, avoiding contact with contaminated foods and materials, and development of modern treatment and vaccine options. Particularly, mandatory monitoring or screening of T. gondii positivity during the pregnancy period in humans should be done. It would be beneficial to replace the French model, especially in the monitoring of disease in humans. In this article, the ecology of toxoplasmosis was reviewed at the base of the "One Health" concept. Keywords: One health, ecology of toxoplasmosis, Toxoplasma gondii, pregnancy, prevention and control, interdisciplinary, struggle "Tek Saglik" konsepti, insanlarin, hayvanlarin ve ekosistemlerin sagligini sürdürülebilir bir sekilde dengelemeyi ve optimize etmeyi esas alan üniversal bir yaklasimdir. Bu yaklasim entegresyon, birlestirici ve holostik temel karakteristikleri ile insanlarin, evcil ve vahsi hayvanlarin, bitkilerin ve içerisinde kendi kendini yenileyebilir ekosistemlerin bulundugu daha genis bir çevrenin sagligini esas alir. Dünyada hem karasal hem de okyanus ekosistemlerinde en yaygin zoonotik karakterli enfeksiyonlardan birisi olan Toxoplasmosis, "Tek Saglik" konsepti için ideal model bir hastaliktir. Toxoplasmosis, zoonotik karakterli, zorunlu hücre içi patojen protozoon Toxoplasma gondii'nin meydana getirdigi bir hastaliktir. Hastalik etkeni T gondii 'nin hayat siklusunda son konagi evcil kedi ve kedigiller, ara konaklari ise insan dahil tüm memeliler, kanatli hayvanlar ve reptillerdir. Hastalik etkeni patojen T gondii 'nin hayat siklusunda kediler hem son konak hem de ara konak vazifesi gördükleri için, ekosistemin kontaminasyonundan da primer öneme sahiptirler. Dolayisiyla evcil kedilerin ve serbest dolasan kedilerin bulundugu ekosistemler, T gondii oocytleriyle enfekte kedi diskilariyla kontamine olurlar. Toxoplasma gondii pozitifligi, karasal ve sucul habitatlarda tüm sicakkanlilarda bilimsel çalismalarla gösterilmistir. Hastalik çiftlik hayvanlarinda ölümlere ve abortlara yol açarak büyük ekonomik kayiplar olusturur. Bununla beraber hastalik, insanlarda özellikle hamile kadinlarda büyük problemlere neden olmaktadir. Gebelikte T gondii konjenital enfeksiyonlari, fetüsün göz ve beyninde lezyonlar, prematüre dogum, intrauterin büyüme geriligi, ates, pnömoni, trombositopeni, oküler lezyonlar, ensefalit ve abort gibi patolojik bozukluklara yol açar. Toxoplasma gondii ile enfekte bir gebede ölüm ve abort, maternal bagisiklik mekanizmasinin tamamen bozulmasi sonucu sekillenmektedir. Toxoplasmosis'e karsi mücadele, üniversal boyutta Dünya Hayvan Sagligi Teskilati, Dünya Saglik Teskilati ve Dünya Gida Teskilati'nin "Tek Saglik" konseptinde koordinasyonunu ve tüm paydas ülkelerde ulusal düzeyde ilgili tüm disiplinlerin bütünlestirici yaklasimlarini gerektirir. Bu baglamda özellikle hastaliktan korunma ve kontrolde, teknigine uygun olarak çevre güvenligi için kedi diskisinin imhasi, kedilerde pozitifligin izlenmesi ve tedavisi, kontamine gida ve malzemelerle temastan kaçinmak, modern tedavi ve asi seçeneklerinin gelistirilmesi ve insan ve hayvanlarda hastaligin zorunlu izlenmesi/taramasi gerekmektedir. Özellikle insanlarda hastaligin izlenmesinde Fransa modeline geçilmesinde yarar vardir. Bu makalede, "Tek Saglik" konseptinde toxoplasmosis'in ekolojisi incelenmistir. Anahtar Kelimeler: Tek saglik, toxoplasmosisin ekolojisi, Toxoplasma gondii, gebelik, korunma ve kontrol, disiplinlerarasi, mücadele</description><subject>Abortion</subject><subject>Analysis</subject><subject>Cats</subject><subject>Ecology</subject><subject>Food contamination</subject><subject>Health aspects</subject><subject>Pregnant women</subject><subject>Prevention</subject><subject>Toxoplasmosis</subject><subject>World health</subject><subject>Zoonoses</subject><issn>1300-6320</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptkD9PwzAUxD2ARCl8BWSJgSmp_6ce24q2iEoZyF65znMwTe0qDoWPTyoYQEI33NPpd284hO4oyQUrxKQ_1nljWggx5YwwnvMp4foCjSgnJFOckSt0ndIbIUoyxUeomwVcnqA7efjA0eEyAF6DaftXvIjBwrHHy2jfkw8NjgFX8TMeW5MOMfk0qWCPX0zT-j1-jiENsA81_IUeAK8gQIvnvsNzs_fpBl060ya4_fExqpaP1WKdbcrV02K2yRpViExwK4GqnbZKEGEL5-RwUiMFBVNYXjvKqWGirmVtjJ4qYdRO7LRjmkk3FXyM7r_fnvfY-uBi3xl78MluZ0WhuWRanan8H2pQDQdvYwDnh_xX4QsbNG3D</recordid><startdate>20231201</startdate><enddate>20231201</enddate><creator>Inci, Abdullah</creator><creator>Sohel, Mahmodul Hasan</creator><creator>Babür, Cahit</creator><creator>Uslu, Sadullah</creator><creator>Karademir, Gupse Kübra</creator><creator>Yürük, Merve</creator><creator>Düzlü, Önder</creator><creator>Kizgin, Alina Denis</creator><creator>Yildirim, Alparslan</creator><general>Galenos Yayinevi Tic. Ltd</general><scope/></search><sort><creationdate>20231201</creationdate><title>An Overview of One Health Concept Focusing on Toxoplasmosis/Tek Saglik Konseptinde Toxoplasmosis'e Genel Bir Bakis</title><author>Inci, Abdullah ; Sohel, Mahmodul Hasan ; Babür, Cahit ; Uslu, Sadullah ; Karademir, Gupse Kübra ; Yürük, Merve ; Düzlü, Önder ; Kizgin, Alina Denis ; Yildirim, Alparslan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g674-43c5e16b9c6404c7ff59c61a541ea7c3df131a24dd5daa9864a6b4b9f2925f843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Abortion</topic><topic>Analysis</topic><topic>Cats</topic><topic>Ecology</topic><topic>Food contamination</topic><topic>Health aspects</topic><topic>Pregnant women</topic><topic>Prevention</topic><topic>Toxoplasmosis</topic><topic>World health</topic><topic>Zoonoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Inci, Abdullah</creatorcontrib><creatorcontrib>Sohel, Mahmodul Hasan</creatorcontrib><creatorcontrib>Babür, Cahit</creatorcontrib><creatorcontrib>Uslu, Sadullah</creatorcontrib><creatorcontrib>Karademir, Gupse Kübra</creatorcontrib><creatorcontrib>Yürük, Merve</creatorcontrib><creatorcontrib>Düzlü, Önder</creatorcontrib><creatorcontrib>Kizgin, Alina Denis</creatorcontrib><creatorcontrib>Yildirim, Alparslan</creatorcontrib><jtitle>Türkiye parazitolojii dergisi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inci, Abdullah</au><au>Sohel, Mahmodul Hasan</au><au>Babür, Cahit</au><au>Uslu, Sadullah</au><au>Karademir, Gupse Kübra</au><au>Yürük, Merve</au><au>Düzlü, Önder</au><au>Kizgin, Alina Denis</au><au>Yildirim, Alparslan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Overview of One Health Concept Focusing on Toxoplasmosis/Tek Saglik Konseptinde Toxoplasmosis'e Genel Bir Bakis</atitle><jtitle>Türkiye parazitolojii dergisi</jtitle><date>2023-12-01</date><risdate>2023</risdate><volume>47</volume><issue>4</issue><spage>256</spage><pages>256-</pages><issn>1300-6320</issn><abstract>The "One Health" concept is a universal approach to sustainably balancing and optimizing the health of humans, animals, and ecosystems. This approach is based on the health of humans, domestic and wild animals, and plants in a wider environment in which self-renewable ecosystems exist, with essential characteristics of integration, unifying and holistic perspective. Toxoplasmosis, one of the most common zoonotic infections in both terrestrial and oceanic ecosystems in the world, is an ideal model disease for the "One Health" approach. Toxoplasmosis is a zoonotic disease caused by the obligate intracellular pathogen protozoan Toxoplasma gondii. In the life cycle of T. gondii, the definitive host is domestic cats and felines, and the intermediate hosts are all mammals (including humans), birds and reptiles. The infected cats have primary importance and play a crucial role in the contamination of habitats in the ecosystems with T. gondii oocysts. Thus, ecosystems with domestic cats and stray cats are contaminated with cat feces infected with T. gondii oocytes. T. gondii positivity has been scientifically demonstrated in all warm-blooded animals in terrestrial and aquatic habitats. The disease causes deaths and abortions in farm animals, resulting in great economic losses. However, the disease causes great problems in humans, especially pregnant women. During pregnancy, it may have effects such as congenital infections, lesions in the eye and brain of the fetus, premature birth, intrauterine growth retardation, fever, pneumonia, thrombocytopenia, ocular lesions, encephalitis, and abortion. The mechanism of death and abortion of the fetus in a pregnant woman infected with T. gondii occurs as a result of complete disruption of the maternal immune mechanism. The struggle against toxoplasmosis requires the universal collaboration and coordination of the World Organization for Animal Health, the World Health Organization and the World Food Organization in the "One Health" concept and integrative approaches of all responsible disciplines. Establishing universal environmental safety with the prevention and control of toxoplasmosis requires the annihilation of the feces of the infected cats using suitable techniques firstly. Then routinely, the monitoring and treatment of T. gondii positivity in cats, avoiding contact with contaminated foods and materials, and development of modern treatment and vaccine options. Particularly, mandatory monitoring or screening of T. gondii positivity during the pregnancy period in humans should be done. It would be beneficial to replace the French model, especially in the monitoring of disease in humans. In this article, the ecology of toxoplasmosis was reviewed at the base of the "One Health" concept. Keywords: One health, ecology of toxoplasmosis, Toxoplasma gondii, pregnancy, prevention and control, interdisciplinary, struggle "Tek Saglik" konsepti, insanlarin, hayvanlarin ve ekosistemlerin sagligini sürdürülebilir bir sekilde dengelemeyi ve optimize etmeyi esas alan üniversal bir yaklasimdir. Bu yaklasim entegresyon, birlestirici ve holostik temel karakteristikleri ile insanlarin, evcil ve vahsi hayvanlarin, bitkilerin ve içerisinde kendi kendini yenileyebilir ekosistemlerin bulundugu daha genis bir çevrenin sagligini esas alir. Dünyada hem karasal hem de okyanus ekosistemlerinde en yaygin zoonotik karakterli enfeksiyonlardan birisi olan Toxoplasmosis, "Tek Saglik" konsepti için ideal model bir hastaliktir. Toxoplasmosis, zoonotik karakterli, zorunlu hücre içi patojen protozoon Toxoplasma gondii'nin meydana getirdigi bir hastaliktir. Hastalik etkeni T gondii 'nin hayat siklusunda son konagi evcil kedi ve kedigiller, ara konaklari ise insan dahil tüm memeliler, kanatli hayvanlar ve reptillerdir. Hastalik etkeni patojen T gondii 'nin hayat siklusunda kediler hem son konak hem de ara konak vazifesi gördükleri için, ekosistemin kontaminasyonundan da primer öneme sahiptirler. Dolayisiyla evcil kedilerin ve serbest dolasan kedilerin bulundugu ekosistemler, T gondii oocytleriyle enfekte kedi diskilariyla kontamine olurlar. Toxoplasma gondii pozitifligi, karasal ve sucul habitatlarda tüm sicakkanlilarda bilimsel çalismalarla gösterilmistir. Hastalik çiftlik hayvanlarinda ölümlere ve abortlara yol açarak büyük ekonomik kayiplar olusturur. Bununla beraber hastalik, insanlarda özellikle hamile kadinlarda büyük problemlere neden olmaktadir. Gebelikte T gondii konjenital enfeksiyonlari, fetüsün göz ve beyninde lezyonlar, prematüre dogum, intrauterin büyüme geriligi, ates, pnömoni, trombositopeni, oküler lezyonlar, ensefalit ve abort gibi patolojik bozukluklara yol açar. Toxoplasma gondii ile enfekte bir gebede ölüm ve abort, maternal bagisiklik mekanizmasinin tamamen bozulmasi sonucu sekillenmektedir. Toxoplasmosis'e karsi mücadele, üniversal boyutta Dünya Hayvan Sagligi Teskilati, Dünya Saglik Teskilati ve Dünya Gida Teskilati'nin "Tek Saglik" konseptinde koordinasyonunu ve tüm paydas ülkelerde ulusal düzeyde ilgili tüm disiplinlerin bütünlestirici yaklasimlarini gerektirir. Bu baglamda özellikle hastaliktan korunma ve kontrolde, teknigine uygun olarak çevre güvenligi için kedi diskisinin imhasi, kedilerde pozitifligin izlenmesi ve tedavisi, kontamine gida ve malzemelerle temastan kaçinmak, modern tedavi ve asi seçeneklerinin gelistirilmesi ve insan ve hayvanlarda hastaligin zorunlu izlenmesi/taramasi gerekmektedir. Özellikle insanlarda hastaligin izlenmesinde Fransa modeline geçilmesinde yarar vardir. Bu makalede, "Tek Saglik" konseptinde toxoplasmosis'in ekolojisi incelenmistir. Anahtar Kelimeler: Tek saglik, toxoplasmosisin ekolojisi, Toxoplasma gondii, gebelik, korunma ve kontrol, disiplinlerarasi, mücadele</abstract><pub>Galenos Yayinevi Tic. Ltd</pub><doi>10.4274/tpd.galenos.2023.38039</doi></addata></record>
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subjects Abortion
Analysis
Cats
Ecology
Food contamination
Health aspects
Pregnant women
Prevention
Toxoplasmosis
World health
Zoonoses
title An Overview of One Health Concept Focusing on Toxoplasmosis/Tek Saglik Konseptinde Toxoplasmosis'e Genel Bir Bakis
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