Trans-Regulation of Alternative IPD-L1/I mRNA Processing by CDK12 in Non-Small-Cell Lung Cancer Cells

Immunotherapy using checkpoint inhibitors targeting the interaction between PD-1 on T cells and PD-L1 on cancer cells has shown significant results in non-small-cell lung cancer (NSCLC). Not all patients respond to the therapy, and PD-L1 expression heterogeneity is proposed to be one determinant for...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cells (Basel, Switzerland) Switzerland), 2023-12, Vol.12 (24)
Hauptverfasser:	Larsen, Trine V, Maansson, Christoffer T, Daugaard, Tina F, Andresen, Brage S, Sorensen, Boe S, Nielsen, Anders L
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer cells Development and progression Genetic aspects Health aspects Ligands (Biochemistry) Lung cancer, Non-small cell Messenger RNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!