Quantitative [.sup.1]H-NMR analysis reveals steric and electronic effects on the substrate specificity of benzoate dioxygenase in Ralstonia eutropha B9

The cis-dihydroxylation of arenes by Rieske dearomatizing dioxygenases (RDDs) represents a powerful tool for the production of chiral precursors in organic synthesis. Here, the substrate specificity of the RDD benzoate dioxygenase (BZDO) in Ralstonia eutropha B9 whole cells was explored using quanti...

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Veröffentlicht in:	Journal of industrial microbiology & biotechnology 2022-05, Vol.49 (3), p.1
Hauptverfasser:	Bent, James S, Clark, Zachary T, Collins, Jonathan A
Format:	Artikel
Sprache:	eng
Schlagworte:	Metabolites Nuclear magnetic resonance spectroscopy Tetracycline Tetracyclines
Online-Zugang:	Volltext
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