Systematic Analysis of 2′-IO/I-Alkyl Modified Analogs for Enzymatic Synthesis and Their Oligonucleotide Properties

Enzymatic oligonucleotide synthesis is used for the development of functional oligonucleotides selected by in vitro selection. Expanding available sugar modifications for in vitro selection helps the functional oligonucleotides to be used as therapeutics reagents. We previously developed a KOD DNA p...

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2023-12, Vol.28 (23)
Hauptverfasser: Ishida, Kenta, Kasahara, Yuuya, Hoshino, Hidekazu, Okuda, Takumi, Obika, Satoshi
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Sprache:eng
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