MLKL deficiency alleviates neuroinflammation and motor deficits in the [alpha]-synuclein transgenic mouse model of Parkinson's disease

Parkinson's disease (PD), one of the most devastating neurodegenerative brain disorders, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN) and deposits of [alpha]-synuclein aggregates. Currently, pharmacological interventions for PD remain inadequate....

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular neurodegeneration 2023-12, Vol.18 (1)
Hauptverfasser:	Geng, Lu, Gao, Wenqing, Saiyin, Hexige, Li, Yuanyuan, Zeng, Yu, Zhang, Zhifei, Li, Xue, Liu, Zuolong, Gao, Qiang, An, Ping, Jiang, Ning, Yu, Xiaofei, Chen, Xiangjun, Li, Suhua, Chen, Lei, Lu, Boxun, Li, Aiqun, Chen, Guoyuan, Shen, Yidong, Zhang, Haibing, Tian, Mei, Zhang, Zhuohua, Li, Jixi
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Gastrointestinal diseases Genetic engineering Neurons Tyrosine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!