Novel 8-Methoxycoumarin-3-Carboxamides with potent anticancer activity against liver cancer via targeting caspase-3/7 and [beta]-tubulin polymerization

In the present study, we explored the potential of coumarin-based compounds, known for their potent anticancer properties, by designing and synthesizing a novel category of 8-methoxycoumarin-3-carboxamides. Our aim was to investigate their antiproliferative activity against liver cancer cells. Towar...

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Veröffentlicht in:	BMC chemistry 2023-12, Vol.17 (1)
Hauptverfasser:	Alzamami, Ahmad, Radwan, Eman M, Abo-Elabass, Eman, Behery, Mohammed El, Alshwyeh, Hussah Abdullah, Al-Olayan, Ebtesam, Altamimi, Abdulmalik S, Attallah, Nashwah G. M, Altwaijry, Najla, Jaremko, Mariusz, Saied, Essa M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Development and progression Health aspects Liver cancer Oncology, Experimental Polymerization Tubulins
Online-Zugang:	Volltext
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