Association of Chromosome 17 Aneuploidy, ITP53/I Deletion, Expression and Its rs1042522 Variant with Multiple Myeloma Risk and Response to Thalidomide/Bortezomib Treatment

The detailed role of the TP53 p.P72R (rs1042522) variant in the etiology and course of multiple myeloma (MM), as well as its association with chromosome 17 aberrations, has not been analyzed in a such a wide range. In our study, we have explored the significance of the p.P72R variant, expression lev...

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Veröffentlicht in:	Cancers 2023-09, Vol.15 (19)
Hauptverfasser:	Popek-Marciniec, Sylwia, Styk, Wojciech, Wojcierowska-Litwin, Magdalena, Chocholska, Sylwia, Szudy-Szczyrek, Aneta, Samardakiewicz, Marzena, Swiderska-Kolacz, Grazyna, Czerwik-Marcinkowska, Joanna, Zmorzynski, Szymon
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment DNA sequencing Gene expression Genes Nucleotide sequencing RNA Tumor proteins
Online-Zugang:	Volltext
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