3D reconstructed brain images reveal the possibility of the ogg1 gene to suppress the irradiation-induced apoptosis in embryonic brain in medaka

The accumulation of oxidative DNA lesions in neurons is associated with neurodegenerative disorders and diseases. Oggl (8-oxoG DNA glycosylase-l) is a primary repair enzyme to excise 7,8-dihydro-8-oxoguanine (8-oxoG), the most frequent mutagenic base lesion produced by oxidative DNA damage. We have...

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Veröffentlicht in:	Journal of radiation research 2022-05, Vol.63 (3), p.319
Hauptverfasser:	Yasuda, Takako, Li, Duolin, Sha, Erge, Kakimoto, Fumitaka, Mitani, Hiroshi, Yamamoto, Hiroshi, Ishikawa-Fujiwara, Tomoko, Todo, Takeshi, Oda, Shoji
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Brain DNA damage Enzymes Gamma rays Genomics Injuries Methylene blue Nervous system diseases Neurons
Online-Zugang:	Volltext
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